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1.
Environ Res ; 259: 119549, 2024 Jul 02.
Artigo em Inglês | MEDLINE | ID: mdl-38964576

RESUMO

Methane (CH4) is the second most abundant greenhouse gas. China is the largest CH4 emitter in the world, with coal mine methane (CMM) being one of the main anthropogenic contributions. Thus, there is an urgent need for comprehensive estimates and strategies for reducing CMM emissions in China. However, the development of effective strategies is currently challenged by a lack of information on temporal variations in the contributions of different CMM sources and the absence of provincial spatial analysis. Here, considering five sources and utilization, we build a comprehensive inventory of China's CMM emissions from 1980 to 2022 and quantify the contributions of individual sources to the overall CMM emissions at the national and provincial levels. Our results highlight a significant shift in the source contributions of CMM emissions, with the largest contributor, underground mining, decreasing from 89% in 1980 to 69% in 2022. Underground abandoned coal mines, which were ignored or underestimated in past inventories, have become the second source of CMM emissions since 1999. From 2011 to 2022, we identified Shanxi, Guizhou, and Shaanxi as the three largest CMM-emitting provinces, while the Emissions Database for Global Atmospheric Research (EDGAR) v8 overestimated emissions from Inner Mongolia, ranking it third. Notably, we observed a substantial decrease (exceeding 1 Mt) in CMM emissions in Sichuan, Henan, Liaoning, and Hunan between 2011 and 2022, which was not captured by EDGAR v8. To develop targeted CMM emission reduction strategies at the provincial level, we classified 31 provinces into four groups based on their CMM emission structures. In 2022, the number of provinces with CMM emissions mainly from abandoned coal mines has exceeded that of provinces with mainly underground mines, which requires attention. This study reveals the characteristics of the source of CMM emissions in China and provides emission reduction directions for four groups of provinces.

2.
Res Dev Disabil ; 150: 104759, 2024 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-38795553

RESUMO

BACKGROUND: Limited knowledge exists regarding the effectiveness of aquatic exercise intervention for improving executive function (EF) in children with autism spectrum disorder (ASD). Additionally, the impact of aquatic exercise on brain-derived neurotrophic factor (BDNF) in children with ASD requires further investigation. AIMS: This study aimed to explore the effects of a 12-week aquatic exercise intervention on core EF and BDNF levels in children with ASD. METHODS AND PROCEDURES: Thirty children with ASD were assigned to an experimental or control group. The experimental group underwent a 12-week aquatic exercise intervention, while the control group engaged in supervised free activities. Pre- and post-intervention assessments measured EF and BDNF levels. OUTCOMES AND RESULTS: The experimental group showed significant improvements (p < 0.05) in inhibition control, cognitive flexibility, and BDNF levels. However, working memory did not significantly improve. The control group exhibited no significant changes in EF or BDNF levels. CONCLUSIONS AND IMPLICATIONS: Aquatic exercise appears to be a beneficial intervention for cognitive development in children with ASD, as it enhances inhibition control, cognitive flexibility, and BDNF levels in children with ASD. Furthermore, the observed improvements in EF following aquatic exercise intervention in children with ASD may be associated with increased BDNF levels.


Assuntos
Transtorno do Espectro Autista , Fator Neurotrófico Derivado do Encéfalo , Função Executiva , Terapia por Exercício , Humanos , Fator Neurotrófico Derivado do Encéfalo/sangue , Fator Neurotrófico Derivado do Encéfalo/metabolismo , Transtorno do Espectro Autista/reabilitação , Transtorno do Espectro Autista/psicologia , Masculino , Feminino , Criança , Terapia por Exercício/métodos , Memória de Curto Prazo/fisiologia , Cognição , Inibição Psicológica , Resultado do Tratamento
3.
Front Public Health ; 12: 1365589, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38605880

RESUMO

Objective: Our network meta-analysis aimed to ascertain the effect of physical activity on the visual-spatial working memory of individuals with mild cognitive impairment and Alzheimer's disease as well as to propose tailored exercise interventions for each group. Methods: Employing a frequentist approach, we performed a network meta-analysis to compare the effectiveness of different exercise interventions in improving the visual-spatial working memory of individuals with mild cognitive impairment and Alzheimer's disease. Subsequently, we explored the moderating variables influencing the effectiveness of the exercise interventions through a subgroup analysis. Results: We included 34 articles involving 3,074 participants in the meta-analysis, comprised of 1,537 participants from studies on mild cognitive impairment and 1,537 participants from studies on Alzheimer's disease. The articles included exhibited an average quality score of 6.6 (score studies) and 6.75 (reaction time [RT] studies), all passing the inconsistency test (p > 0.05). In the mild cognitive impairment literature, mind-body exercise emerged as the most effective exercise intervention (SMD = 0.61, 95% CI: 0.07-1.14). In Alzheimer's disease research, aerobic exercise was identified as the optimal exercise intervention (SMD = 0.39, 95% CI: 0.06-0.71). Conclusion: The results of the subgroup analysis suggest that the most effective approach to enhancing the visual-spatial working memory of individuals with mild cognitive impairment entails exercising at a frequency of three or more times per week for over 60 min each time and at a moderate intensity for more than 3 months. Suitable exercise options include mind-body exercise, multicomponent exercise, resistance exercise, and aerobic exercise. For individuals with Alzheimer's disease, we recommend moderately intense exercise twice per week for over 90 min per session and for a duration of 3 months or longer, with exercise options encompassing aerobic exercise and resistance exercise.


Assuntos
Doença de Alzheimer , Disfunção Cognitiva , Humanos , Doença de Alzheimer/terapia , Disfunção Cognitiva/terapia , Disfunção Cognitiva/psicologia , Exercício Físico , Memória de Curto Prazo , Metanálise em Rede
4.
Sci Rep ; 14(1): 8753, 2024 Apr 16.
Artigo em Inglês | MEDLINE | ID: mdl-38627459

RESUMO

In response to the global trend of climate change, it is important to accurately quantify emissions of fully fluorinated greenhouse gases (FFGHGs, referring to SF6/NF3/CF4/C2F6/C3F8/c-C4F8 here). Atmospheric observation-based top-down methods and activity-based bottom-up methods are usually used together to estimate FFGHG emissions at the global and regional levels. In this work, emission gaps at global and regional levels are discussed among top-down studies, between the top-down and bottom-up FFGHG emissions, and among bottom-up emissions. Generally, trends and magnitudes of individual FFGHG emissions among top-down estimates are close to each other within the uncertainties. However, global bottom-up inventories show discrepancies in FFGHG emissions among each other in trends and magnitudes. The differences in emission magnitudes are up to 93%, 90%, 88%, 83%, 87%, and 85% for SF6, NF3, CF4, C2F6, C3F8, and c-C4F8, respectively. Besides, we reveal the insufficient regional TD studies and the lack of atmospheric observation data/stations especially in areas with potential FFGHG emissions. We make recommendations regarding the best practices for improving our understanding of these emissions, including both top-down and bottom-up methods.

5.
Psychol Res Behav Manag ; 17: 305-315, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38292255

RESUMO

Purpose: The deleterious impact of aggressive behavior on college students necessitates urgent mitigation. To explore the influencing factors and underlying mechanisms of aggressive behaviors among college students, this study aims to validate the mediating roles of life satisfaction, meaning in life, and depression by examining the relationship between physical exercise and aggressive behaviors among college students. Methods: The Physical Activity Rating Scale-3 (PARS-3), Satisfaction with Life Scale, Meaning in Life Questionnaire, Chinese Version DASS-21 and 12-item Perception of Aggression Scale (POAS) were tested on 1596 college students from three universities in western China, and SPSS 26.0 and Mplus 8.3 were used for analysis. Results: Physical exercise exhibited a significant negative correlation with both aggressive behaviors and depression among college students (r = -0.57, P < 0.001; r = -0.36, P < 0.001), as well as a significant positive correlation with life satisfaction and meaning in life (r = 0.45, P < 0.001; r = 0.27, P < 0.001). Regarding the impact of physical exercise on aggressive behaviors among college students, the mediating effects of life satisfaction, meaning in life, and depression were significant. The respective effect sizes were -0.11, -0.08, and -0.03. The chain mediation effect of life satisfaction through depression was also found to be significant, with an effect size of -0.02. Conclusion: This study elucidates the mechanistic pathways through which physical exercise influences aggressive behavior among college students. The relationship between physical exercise and aggressive behavior is influenced by the individual mediating effects of life satisfaction, meaning in life, and depression, as well as the chain mediation effect of life satisfaction through depression. These findings provide a novel perspective on the prevention and intervention of aggressive behaviors among college students in China and potentially worldwide. This suggests that more attention should be paid to the organic combination of students' physical activity and mental health education.

6.
Children (Basel) ; 11(1)2024 Jan 11.
Artigo em Inglês | MEDLINE | ID: mdl-38255398

RESUMO

Children with intellectual disabilities often face challenges in balance ability and lower limb muscle strength, which negatively impact their daily lives and motor function. Therefore, it is crucial to enhance the balance ability and lower limb muscle strength of children with intellectual disabilities. This study aimed to investigate the effects of a 12-week aquatic exercise and floor curling intervention on the balance ability and lower limb muscle strength of children with intellectual disabilities. Forty-two participants were randomly assigned to the aquatic exercise group, floor curling group, and control group. The aquatic exercise and floor curling groups received a 12-week intervention, while the control group engaged in supervised free activities. The participants' balance ability and lower limb muscle strength were assessed using the Berg Balance Scale and a muscle strength testing device before and after the intervention. The results showed significant improvements in balance ability and lower limb muscle strength for both the aquatic exercise group and the floor curling group after the intervention. The aquatic exercise group demonstrated an average improvement of 10.84% in balance ability and an overall average improvement of 16.28% in lower limb muscle strength. The floor curling group showed an average improvement of 9.04% in balance ability and an overall average improvement of 15.67% in lower limb muscle strength. These improvement results were statistically significant (p < 0.05) and ranged from medium to large effect sizes (d = 0.5~0.8). The findings of this study validate the positive effects of aquatic exercise and floor curling on the balance ability and lower limb muscle strength of children with intellectual disabilities. These interventions can be considered effective approaches for functional rehabilitation in children with intellectual disabilities.

7.
Environ Sci Technol ; 57(48): 19487-19496, 2023 Dec 05.
Artigo em Inglês | MEDLINE | ID: mdl-37948623

RESUMO

Fully fluorinated greenhouse gases (FFGHGs), including sulfur hexafluoride (SF6), nitrogen trifluoride (NF3), and perfluorocarbons (PFCs), have drawn attention because they have long atmospheric lifetimes (up to thousands of years) and high global warming potential. Targeting SF6, NF3, and four PFCs (CF4, C2F6, C3F8, and c-C4F8), this study projects future FFGHG emission patterns in China, explores their mitigation potential, and evaluates the effects of FFGHG emission reduction on the achievement of the country's carbon neutrality goal and climate change. FFGHG emissions are expected to increase consistently, ranging from 506 to 1356 Mt CO2-eq yr-1 in 2060 under the business-as-usual (BAU) scenario. If mitigation strategies are sufficiently employed, FFGHG emissions under three mitigation scenarios: Technologically Feasible 2030, Technologically Feasible 2050, and Technologically Feasible 2060, will eventually decrease to approximately 49-78, 70-110, and 98-164 Mt CO2-eq yr-1 in 2060, respectively, compared to the BAU scenario. Extensive implementation of FFGHG emission mitigation technologies will curb temperature rise by 0.008-0.013 °C under the slowest mitigation scenario, compared to 0.013-0.026 °C under the BAU scenario. Well-coordinated policies and reforms on FFGHG emission mitigation are recommended to prevent potential adverse effects on the climate to a certain extent.


Assuntos
Fluorocarbonos , Gases de Efeito Estufa , Mudança Climática , Efeito Estufa , Dióxido de Carbono/análise , Fluorocarbonos/análise , China
8.
ERJ Open Res ; 9(5)2023 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-37850211

RESUMO

Background: The cough reflex is a protective reflex of the human body. Increases or decreases in cough reflex sensitivity may be related to chronic cough, aspiration pneumonia and other diseases. The right primary somatosensory cortex (RS1) is the main activation centre for the urge to cough. Here, we discuss the effects of transcranial direct current stimulation (tDCS) of RS1 on the cough reflex and urge to cough. In addition, we explored the role of the left dorsolateral prefrontal cortex (lDLPFC) in cough using tDCS. Methods: 24 healthy young adults completed this pilot randomised controlled crossover experiment. Each person was tested three times, receiving, in random order, anodal tDCS of RS1 or lDLPFC or sham stimulation. The current intensity was set to 2 mA, the stimulation time was 30 min and the interval between any two stimuli was ≥1 week. After each intervention, the citric acid cough challenge test was used immediately to assess the urge to cough and cough reflex sensitivity. Results: The cough reflex thresholds, expressed as LogC2 and LogC5, were significantly reduced after RS1 anodal stimulation compared to sham stimulation, accompanied by increased urge-to-cough sensitivity (urge-to-cough log-log slope 1.19±0.40 point·L·g-1 versus 0.92±0.33 point·L·g-1, p=0.001), but the threshold for the urge to cough did not change significantly. There were no significant changes in the urge to cough and cough reflex sensitivity after tDCS anodal lDLPFC stimulation. Conclusion: Anodal tDCS stimulation of the RS1 can increase urge-to-cough sensitivity and reduce cough reflex threshold. The effects of tDCS on cough reflex, as well as the underlying mechanisms driving those effects, should be explored further.

9.
Front Psychol ; 14: 1103003, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-36874874

RESUMO

Introduction: Physical activity interventions improve cognitive performance, especially visuospatial working memory (VSWM). However, evidence on the effects of these interventions in children, adolescents, and older adults remains scant. This meta-analysis aimed to identify the effects of physical activity on VSWM improvement in healthy individuals and the best exercise intervention program to improve VSWM capacity. Methods: We searched for randomized controlled trials (RCTs) of exercise interventions targeting VSWM in healthy individuals from Web of Science, MEDLINE, BIOSIS Previews, PubMed, China National Knowledge Infrastructure, and Wanfang Data (Chinese) databases, from inception to August 20, 2022. Results: Among 21 articles (1,595 healthy participants), the heterogeneity test statistic was I2 = 32.3%, p = 0.053. The mean quality scores of the included articles were 6.9 points (reaction time [RT] studies) and 7.5 points (Score studies). Moreover, 28 RCTs were included (10 RT studies and 18 Score studies), and the subgroup analysis found significant effects for elderly participants, children, interventions involving a higher level of cognitive engagement, low and moderate exercise intensity, chronic exercise, exercise duration ≥60 min, and exercise period ≥90 days. Physical activity had a small but significant positive impact on VSWM in healthy individuals. Current evidence confirms the effects of physical activity on VSWM capacity only in children and seniors but not in young adults. Other age groups, including adolescents and middle-aged adults, have not been studied. Prescription of interventions involving high-level cognitive engagement, low and moderate exercise intensity, chronic exercise, exercise for >30 min per session, and exercise for more than 3 months is recommended for children and seniors. Discussion: Future RCTs would be to fill the gap in studies on adolescents and middle-aged adults, and report detailed exercise intervention programs about different age groups.Systematic Review Registration: PROSPERO (https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42022354737). INPLASY (https://doi.org/10.37766/inplasy2022.8.0053).

10.
J Environ Sci (China) ; 124: 723-734, 2023 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-36182177

RESUMO

Understanding the emission sources of volatile organic compounds (VOCs) is critical for air pollution mitigation. Continuous measurements of atmospheric VOCs were conducted from January to February in Hangzhou in 2021. The average measured concentration of total VOCs (TVOCs) was 38.2 ± 20.9 ppb, > 42% lower than that reported by previous studies at the urban center in Hangzhou. The VOC concentrations and proportions were similar between weekdays and weekends. During the long holidays of the Spring Festival in China, the concentrations of TVOCs were ∼50% lower than those during the regular days, but their profiles showed no significant difference (p > 0.05). Further, we deduced that aromatics and alkenes were the most crucial chemicals promoting the formation of O3 and secondary organic aerosol (SOA) in Hangzhou. According to interspecies correlations, combustion processes and solvent use were inferred as major VOC emission sources. This study provides implications for air quality improvements before and during the upcoming Asian Games that will be hosted in Hangzhou in 2022.


Assuntos
Poluentes Atmosféricos , Ozônio , Compostos Orgânicos Voláteis , Aerossóis/análise , Poluentes Atmosféricos/análise , Alcenos/análise , China , Monitoramento Ambiental , Ozônio/análise , Solventes , Compostos Orgânicos Voláteis/análise
11.
Front Public Health ; 11: 1309824, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-38259776

RESUMO

Background: Healthy lifestyles are considered important means to reduce the burden of diseases. This cross-sectional study was conducted based on the Ecological Model of Health Behavior (EMHB) to analyze the factors associated with the health-promoting lifestyles of Chinese residents. Methods: We carried out a cross-sectional investigation in July 2023. Our investigated factors included social-demographic characteristics (including sex, age, education level, employment status, marital status, personal monthly income, and daily behavioral habits [which were measured by a questionnaire)], health literacy [which was measured by the Chinese version of the Health Literacy Scale Short-Form scale (HLS-SF12)], and family health [which was measured by the Chinese version of the Short-Form of the Family Health Scale (FHS-SF)]. Our outcome was health promoting lifestyle, which was measured by a revised version of Health Promoting Lifestyle Profile-II (HPLP-IIR). Data were analyzed using stepwise regression. Results: A total of 1,402 participants were enrolled. Higher scores of HLS-SF12 (ß = 0.467), having regular exercise (ß = 0.212), and regular physical examination (ß = 0.088) were associated with better health-prompting lifestyles. However, older age (≥60 years) (ß = -0.046), drinking (ß = -0.066), and sleeping time (5-6 h/day) (ß = -0.048) were associated lower levels of health-prompting lifestyles. Living with family (ß = 0.077), FHS-SF (ß = 0.104), and married (ß = -0.077) were significant influencers. Unemployed (ß = -0.048), receiving retirement pay (ß = -0.053), and economic support provided by parents (ß = 0.094) were associated with better health-prompting lifestyles. There were multiple influencing factors of the six dimensions of the HPLP-IIR. Our findings indicate that community residents with higher health literacy, better family health, and health-related behaviors tend to have better health-promoting lifestyles. Conclusion: Our findings have confirmed the complex impacts of social-ecological factors on health-promoting lifestyles, which may help policy makers with health-promotion strategies making and also help researchers to control for confounding in study design.


Assuntos
Estilo de Vida Saudável , Projetos de Pesquisa , Humanos , Estudos Transversais , Comportamentos Relacionados com a Saúde , Pessoal Administrativo
12.
Front Psychol ; 13: 964169, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-36438387

RESUMO

Background and aims: Academic burnout is harmful to college students, their institutions of learning, and society at large. While research has shown that physical exercise may be associated with reduced academic burnout, the underlying mechanisms require further exploration. This study explored the relationship between physical exercise and academic burnout in a sample of college students, with a focus on the serial mediating roles of self-efficacy and resilience. Methods: This study adopted a cross-sectional survey approach among a sample of undergraduate college students in China. We recruited 1,270 participants in the second half of the 2021-2022 academic year (476 men and 794 women), all of whom completed questionnaires containing the Physical Activity Rating Scale, Academic Burnout Scale for College Students, 10-item General Self-Efficacy Scale, and 25-item Connor-Davidson Resilience Scale. We then subjected the collected data to a series of statistical analyses. Results and conclusion: Physical exercise was significantly and negatively associated with academic burnout and its three subfactors (i.e., emotional exhaustion, improper behavior, and low personal achievement). Participants in the high physical exercise group showed lower levels of academic burnout than those in the moderate and low physical exercise groups. Finally, our serial mediation model showed that physical exercise had a significant direct effect on academic burnout (ß = -0.1104, 95% CI = [-0.1421, -0.0791]) in addition to significant indirect effects on academic burnout via self-efficacy and resilience (ß = -0.0802, 95% CI = [-0.1088, -0.0527]); the more exercise participation, the lower the academic burnout among college students. These findings suggest that physical exercise is an important interventional target when aiming to reduce academic burnout.

13.
Environ Sci Process Impacts ; 24(11): 1968-1981, 2022 Nov 16.
Artigo em Inglês | MEDLINE | ID: mdl-36000414

RESUMO

Volatile organic compounds (VOCs) are important precursors of severe pollution of ozone (O3) and secondary organic aerosols in China. Fully understanding the VOCs emission is crucial for making regulations to improve air quality. This study reviews the published studies on atmospheric VOCs concentration observations in China and observation-based estimation of China's VOCs emission strengths and emission source structures. The results reveal that direct sampling and stainless-steel-tank sampling are the most commonly used methods for online and offline observations in China, respectively. The GC-MS/FID is the most commonly used VOCs measuring instrument in China (in 60.8% of the studies we summarized). Numerous studies conducted observation campaigns in urban areas (76.2%) than in suburban (17.1%), rural (18.1%), and background areas (14.3%) in China. Moreover, observation sites are largely set in eastern China (83.8%). Though there are published studies reporting observation-based China's VOCs emission investigation, these kinds of studies are still limited, and gaps are found between the results of top-down investigation and bottom-up inventories of VOCs emissions in China. In order to enhance the observation-based VOCs emission investigations in China, this study suggests future improvements including: (1) development of VOCs detection techniques, (2) strengthening of atmospheric VOCs observations, (3) improvement of the accuracy of observation-based VOCs emission estimations, and (4) facilitation of better VOCs emission inventories in China.


Assuntos
Poluentes Atmosféricos , Ozônio , Compostos Orgânicos Voláteis , Compostos Orgânicos Voláteis/análise , Poluentes Atmosféricos/análise , Monitoramento Ambiental , Ozônio/análise , China
14.
Environ Res ; 214(Pt 2): 113944, 2022 11.
Artigo em Inglês | MEDLINE | ID: mdl-35870498

RESUMO

China has shut down and abandoned a substantial number of coal mines since 1999, which have been releasing methane (CH4) for many years. However, the characteristics of China's abandoned mine methane (AMM) emissions are still unclear; this is a concerning knowledge gap because coal mines are the largest contributor to China's anthropogenic CH4 emissions. This study used two methods to estimate China's historical AMM emissions over the past 40 years (1980-2020) and to project its AMM emissions to 2060 which is the target year for China's carbon neutrality goal. The results show that China's AMM emissions increased substantially from 0.11 ± 0.03 million tons per year (Mt/yr) (3.1 ± 0.84 Mt/yr CO2-eq) in 1980 to 4.7 ± 0.94 Mt/yr (131 ± 26 Mt/yr CO2-eq) in 2020. An accelerated growth rate was found during 1998-2005, with AMM emissions rapidly increasing by approximately three times, which was consistent with the high number of mine shutdowns. In 2019, we found that AMM emissions had become the fourth largest anthropogenic source in China, higher than the national anthropogenic CH4 emissions of individual United Nations Framework Convention on Climate Change Annex I countries excluding the United States of America and the Russian Federation. If unabated, China's AMM emissions are projected to peak at 8.7 ± 2.6 Mt/yr in 2040 and reach approximately one-third of China's anthropogenic carbon dioxide emissions in 2060. This study reveals that understanding AMM emissions can help more accurately quantify China's total CH4 emissions and guide their future mitigation.


Assuntos
Dióxido de Carbono , Metano , Dióxido de Carbono/análise , Mudança Climática , Carvão Mineral , Metano/análise , Mineração , Estados Unidos
15.
Respir Res ; 23(1): 99, 2022 Apr 21.
Artigo em Inglês | MEDLINE | ID: mdl-35449062

RESUMO

BACKGROUND: Chronic cough is prevalent in the clinic. The existing therapies are mostly limited to medical treatment, with poor curative effects and serious side effects. Studies have suggested that the right dorsolateral prefrontal cortex (rDLPFC) may play an active role in the inhibitory pathway of cough elicitation. Thus, this study explored the effect of transcranial direct current stimulation (tDCS) on the rDLPFC activation in relation to cough reflex and urge-to-cough sensitivity. METHODS: Twenty-three healthy young adults completed the experiment. Participants randomly received tDCS anodal stimulation, cathodal stimulation, and sham stimulation, and the interval between every two stimuli was at least one week. The tDCS (2 mA, 30 min) stimulated brain rDLPFC region. After tDCS intervention, cough reflex threshold and urge-to-cough were evaluated immediately by inhalation of citric acid-saline solution. RESULTS: Compared with sham stimulation, the cough reflex thresholds logC2 and logC5 have increased under tDCS anodal stimulation (1.78 ± 0.55 g/L vs. 1.57 ± 0.57 g/L, p < 0.05; 1.92 ± 0.53 g/L vs. 1.67 ± 0.56 g/L, p < 0.05), accompanied by the increase of the urge-to-cough threshold LogCu (0.76 ± 0.53 g/L vs. 0.47 ± 0.44 g/L, p < 0.05). In contrast, the urge-to-cough sensitivity expressed as UTC slope was not significantly changed (1.21 ± 0.86 point·L/g vs. 1.00 ± 0.37 point·L/g, p > 0.05), and there were no apparent changes in cough reflex thresholds Log C2 and logC5, urge-to-cough threshold LogCu, and urge-to-cough sensitivity UTC slope under tDCS cathodal stimulation, compared with sham stimulation. CONCLUSIONS: This study found that anodal tDCS stimulation of rDLPFC could significantly decrease cough reflex sensitivity, accompanied by the increase of urge-to-cough threshold. Further investigations targeting different brain regions using multiple central intervention techniques to explore the underlying mechanisms are warranted. Trial registration The study protocol was registered for the clinical trial in China (registration number: ChiCTR2100045618).


Assuntos
Estimulação Transcraniana por Corrente Contínua , Tosse/terapia , Córtex Pré-Frontal Dorsolateral , Nível de Saúde , Humanos , Reflexo , Estimulação Transcraniana por Corrente Contínua/métodos , Adulto Jovem
16.
Animals (Basel) ; 12(4)2022 Feb 17.
Artigo em Inglês | MEDLINE | ID: mdl-35203210

RESUMO

The t9,c12,c15-C18:3 as an isomer of α-linolenic acid (c9,c12,c15-C18:3; ALA), has been recently detected in milk, but has not been found in the rumen. This study hypothesized that it may be a biohydrogenation product of ALA in rumen and aimed to explore whether it was present in the rumen and help to understand the rumen biohydrogenation mechanisms of ALA. The in vitro experiment included two treatments, a control check (CK group) with 50 µL ethanol added, and ALA group with 50 µL ethanol and 2.6 mg ALA (ALA addition calculated by 1.30% of dry matter base of diet); each sample of fermentation fluid had the composition of C18 fatty acids analyzed at 0, 0.5, 1, 2, 3, 4, 5, and 6 h. The results showed that no t9,c12,c15-C18:3 was detected in the CK group, but ALA addition increased the concentration of t9,c12,c15-C18:3 in fermentation fluid. The content of t9,c12,c15-C18:3 peaked 1 h after fermentation, then declined gradually. At 1 h, no t9c12c15-C18:3 was detected in the fermentation fluid of the CK treatment. The results suggested that ALA converted to the isomer t9,c12,c15-C18:3 through biohydrogenation in the rumen. The addition of ALA can also increase the concentration of t9,c12-C18:2, c9,t11-C18:2, c12-C18:1, t11-C18:1, t9-C18:1, and c6-C18:1 in fermentation fluid. It was concluded using an in vitro experiment that t9,c12,c15-C18:3 was a product of rumen biohydrogenation of ALA.

17.
Front Psychol ; 13: 1104143, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-36698612

RESUMO

Introduction: Athlete burnout has many potential negative effects on athletes' sporting performance and careers. Maintaining and promoting the coach-athlete relationship to meet athletes' basic psychological needs is one way to reduce burnout. Existing studies of the correlation between coach-athlete relationships and athlete burnout have mainly focused on the coaches' leadership style, with little attention given to relationship-maintenance strategies and the mechanism of athlete burnout from the athletes' perspective. Methods: Using an online survey of 256 adolescent athletes, we explore the relationship between relationship-maintenance strategies and athlete burnout, including the potential mediating effects of the coach-athlete relationship and basic psychological needs satisfaction. Results: (1) Athletes' relationship-maintenance strategies negatively predicted athlete burnout. (2) Besides the direct effect, we found evidence to support three mediation paths: (a) the coach-athlete relationship, (b) basic psychological needs satisfaction, and (c) both as serial mediators. Discussion: These findings enhance understanding of the mechanism of athlete burnout, demonstrating the influence of factors beyond the coach's role. The study also provides a theoretical basis for practical intervention by coaches, athletes, and sports organizations to reduce athlete burnout by focusing on athletes' perspectives.

18.
Front Microbiol ; 12: 760528, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34867889

RESUMO

Flaxseed is rich in α-linolenic acid (ALA) and can increase omega-3 polyunsaturated fatty acid in the milk of dairy cows. However, the response of rumen fermentation to different forms of flaxseed supplementation is unknown. This study aimed to investigate the effect of different forms of flaxseed on the fatty acid profile, fermentation, and composition of bacteria in the rumen of dairy cows. In total, 30 Holstein dairy cows were selected and randomly assigned into three groups (10/group). Cows were fed a basal diet (control check; CK) or basal diets supplemented with either 1,500 g per day whole flaxseed (WF) or 1,500 g per day ground flaxseed (GF). The WF group had the highest ALA content in rumen fluid, whereas no difference was found between the CK and GF groups. However, the molar proportion of acetate increased in the WF and GF groups and was the highest in the GF group, and a similar trend was shown by propionate, isobutyrate, butyrate, isovalerate, and valerate (CK < WF < GF). The abundance of Ruminococcaceae_NK4A214_group, Christensenellaceae_R-7_group, and Eubacterium_coprostanoligenes_group also showed the same trend (CK < WF < GF). Different forms of flaxseed release ALA by different mechanisms in the rumen, and the molar proportions of volatile fatty acids and the bacterial composition were potentially influenced mainly by the amount of ALA released into the rumen.

19.
Front Psychol ; 12: 658106, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34149544

RESUMO

Test anxiety caused by intolerance of uncertainty has a negative impact on the physical and mental health of student athletes, especially in the context of the coronavirus disease 2019 (COVID-19) pandemic. A total of 556 grade three high school student athletes in Chongqing, China, were investigated using the Test Anxiety Scale (TAS), Intolerance of Uncertainty Scale-12 (IUS-12), Perceived Social Support Scale, and Coping Style Scale for Middle School Students. Results reveal that more than half the student athletes experienced test anxiety, and the severity was above average during the COVID-19 pandemic. There was a significant correlation between intolerance of uncertainty, perceived social support, coping style, and test anxiety. A positive correlation was found between test anxiety, intolerance of uncertainty, and coping style toward emotions, and a negative correlation between test anxiety, perceived social support, and coping style toward problems. Intolerance of uncertainty has a direct predictive effect on test anxiety, and perceived social support and coping style play a chain mediator role between intolerance of uncertainty and test anxiety. By constructing the mediating effect model, we can, to some extent, reveal the mechanism of the influence of intolerance of uncertainty on test anxiety. This study has a certain reference value for the prevention of test anxiety in student athletes in the context of the COVID-19 pandemic.

20.
Environ Int ; 156: 106710, 2021 11.
Artigo em Inglês | MEDLINE | ID: mdl-34144364

RESUMO

Accurate measurement and estimation on the trends and spatial distributions of VOCs emissions in China are critical to establishing efficient local or regional pollution control measures, while less is known about the discrepancies on VOCs emissions estimated by previous studies. In this study, two of the estimation approaches including the bottom-up and top-down methods have been reviewed with the data collected from many studies. The approaches demonstrated that the total anthropogenic VOCs emissions in China have been increasing since 1949. The contributions of industrial and solvent use to total VOCs emissions have been increasing since 2000, whereas the contributions of transportation sector have shown a decreasing trend since 2000. The contributions of fuel combustion have also been decreasing since 1950. The gaps of emission estimates for the industry and solvent use were 99.3 ± 22.7% and 81.5 ± 41.8%, respectively, which distributed in much wider ranges than other sources (e.g. 28.9 ± 16.7% for fuel combustion). In comparison to the top-down method, larger variations on the annual VOCs emission estimates were seen using the bottom-up method that comprised different data sources. For the view of spatial pattern, most hot emission estimate spots were concentrated in the eastern China, consistent to their relatively stronger strengths in the industrialization and urbanization. Although the total VOCs emission in China has been continuously increasing during 2008-2016, the VOCs emissions per gross domestic production (GDP) showed a decreasing trend. As for individual compounds, large discrepancy was seen on formaldehyde, with the coefficient of variation (CV) ranged from 37% to 128% over the years. In overall of view, the importance of industrial process and solvent use is increasing. More focuses must be made to these two sources. Emissions of individual compound, particularly those of oxygenated VOCs, were not completely determined and should be better quantified.


Assuntos
Poluentes Atmosféricos , Compostos Orgânicos Voláteis , Poluentes Atmosféricos/análise , China , Monitoramento Ambiental , Urbanização , Compostos Orgânicos Voláteis/análise
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