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1.
J Enzyme Inhib Med Chem ; 36(1): 2139-2159, 2021 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-34628990

RESUMO

Inflammation and disease are closely related. Inflammation can induce various diseases, and diseases can promote inflammatory response, and two possibly induces each other in a bidirectional loop. Inflammation is usually treated using synthetic anti-inflammatory drugs which are associated with several adverse effects hence are not safe for long-term use. Therefore, there is need for anti-inflammatory drugs which are not only effective but also safe. Several researchers have devoted to the research and development of effective anti-inflammatory drugs with little or no side effects. In this review, we studied some small molecules with reported anti-inflammatory activities and hence potential sources of anti-inflammatory agents. The information was retrieved from relevant studies published between January 2019 and May, 2021 for review. This review study was aimed to provide relevant information towards the design and development of effective and safe anti-inflammation agents.


Assuntos
Anti-Inflamatórios não Esteroides/uso terapêutico , Inflamação/tratamento farmacológico , Bibliotecas de Moléculas Pequenas/uso terapêutico , Anti-Inflamatórios não Esteroides/síntese química , Anti-Inflamatórios não Esteroides/química , Humanos , Estrutura Molecular , Bibliotecas de Moléculas Pequenas/síntese química , Bibliotecas de Moléculas Pequenas/química
2.
Artigo em Chinês | WPRIM (Pacífico Ocidental) | ID: wpr-255076

RESUMO

<p><b>OBJECTIVE</b>Dermabrasion has been of great value in plastic surgery. Dermabrasion was developed for a specific indication; however, within a very short time, the concept of dermabrasion found wide applicability. This study was to investigate the application of dermabrasion in the treatment of acne scars.</p><p><b>METHODS</b>From Feb. 1996 to May 2004, a total of 110 patients with acne scar were treated with dermabrasion.</p><p><b>RESULTS</b>Postoperatively, the curative results were achieved in 45 cases; good results in 40 cases and effective results in 25 cases. The study revealed that the patients at 18-46 years of age have good results.</p><p><b>CONCLUSIONS</b>Dermabrasion is a good and safe technique to treat the scar of acne.</p>


Assuntos
Adolescente , Adulto , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Adulto Jovem , Acne Vulgar , Cirurgia Geral , Cicatriz , Cirurgia Geral , Dermabrasão , Métodos , Face , Cirurgia Geral
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