RESUMO
The emergence of new body technologies has led to the deconstruction of a cosmetically enhanced celebrity body into a bioinformational data-self, which becomes a surveilled subject quantified through biometric proximity. Evidently, the bodies of Indian Hindi film actresses evolve into material sites for the discursive encoding, bioinformational performativity and transference of disciplining hegemonic beauty ideals. In this age of information, the celebrity capital and postdigital positionality of celebrity bodies grant their bioinformational spectacular performance with a potential biologising affect for the further corporealisation of popular body aesthetics. Drawing on the maxims of new materialisms and neoliberal subjectivities, the article seeks to decipher the entanglement between the cultural economy of Indian Hindi film stars, their enhanced biometric dynamics and biologising spectacular performativity. Indian Hindi film industry, media, tabloids, magazines, celebrity culture and aesthetic clinics situate Indian Hindi film actresses under vigilant surveillance and simulcast their cosmetic consumption and technologically enhanced bodies across the visual-online attention economy. The present study, therefore exposes the enhanced bodies and biometric dynamics of Indian Hindi film actresses as the human and non-human agentic forms of industrialised cosmetic culture and neoliberal bioconsumerism.
RESUMO
BACKGROUND: Nowadays, fraction flow reserve (FFR) is being discussed in every percutaneous coronary intervention (PCI) capable hospitals. Owing to recent development in the medical field, FFR-guided PCI should be able to find a place in Interventional Cardiology. At present, the importance of FFR to stratify patients who require PCI has seldom systematically been investigated. In this analysis, we aimed to compare the major adverse cardiac events (MACEs) mainly in patients with stable coronary artery disease (CAD) to whom PCI was recommended and deferred respectively based on the FFR value. METHODS: Electronic databases were searched for studies comparing FFR-recommended versus FFR-deferred coronary stenting. Long-term MACEs, mortality, and myocardial infarction (MI) were considered as the clinical endpoints in this analysis. Odds ratios (ORs) with 95% confidence intervals (CIs) were calculated and the analyses were carried out by the latest version of the RevMan software. RESULTS: A total number of 1753 patients (670 patients were revascularized, whereas 1083 patients were deferred from revascularization based on the FFR value) were analyzed. Current results showed MACEs and MI were significantly higher in the FFR-recommended PCI group with OR 1.34 (95% CI: 1.05-1.72; Pâ=â.02) and OR 1.73 (95% CI: 1.19-2.51; Pâ=â.004, Iâ=â0%), respectively. However, mortality was similarly manifested with OR 1.23 (95% CI: 0.92-1.63; Pâ=â.16, Iâ=â0%). CONCLUSION: Significantly higher MACEs were observed in patients to whom PCI was recommended compared to those patients who were deferred from undergoing PCI based on the FFR values. Therefore, FFR might indeed be an important decision-making procedural tool, which should be used to stratify stable CAD patients with an advanced disease and who are qualified candidates for PCI. Further research should confirm this hypothesis.
Assuntos
Tomada de Decisão Clínica/métodos , Doença da Artéria Coronariana/fisiopatologia , Reserva Fracionada de Fluxo Miocárdico/fisiologia , Seleção de Pacientes , Intervenção Coronária Percutânea/métodos , Idoso , Doença da Artéria Coronariana/mortalidade , Doença da Artéria Coronariana/cirurgia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Infarto do Miocárdio/etiologia , Infarto do Miocárdio/mortalidade , Razão de Chances , Intervenção Coronária Percutânea/mortalidade , Complicações Pós-Operatórias/etiologia , Complicações Pós-Operatórias/mortalidade , Fatores de Risco , Stents , Resultado do TratamentoRESUMO
BACKGROUND: We aimed to systematically compare Major Adverse Cardiac Events (MACEs) and mortality following Percutaneous Coronary Intervention (PCI) in patients with and without Chronic Obstructive Pulmonary Diseases (COPD) through a meta-analysis. METHODS: Electronic databases (Cochrane library, EMBASE and Medline/PubMed) were searched for English publications comparing in-hospital and long-term MACEs and mortality following PCI in patients with a past medical history of COPD. Statistical analysis was carried out by Revman 5.3 whereby Odds Ratio (OR) and 95% Confidence Intervals (CI) were considered the relevant parameters. RESULTS: A total number of 72,969 patients were included (7518 patients with COPD and 65,451 patients without COPD). Results of this analysis showed that in-hospital MACEs were significantly higher in the COPD group with OR: 1.40, 95% CI: 1.19-1.65; P = 0.0001, I2 = 0%. Long-term MACEs were still significantly higher in the COPD group with OR: 1.58, 95% CI: 1.38-1.81; P = 0.00001, I2 = 29%. Similarly, in-hospital and long-term mortality were significantly higher in patients with COPD, with OR: 2.25, 95% CI: 1.78-2.85; P = 0.00001, I2 = 0% and OR: 2.22, 95% CI: 1.33-3.71; P = 0.002, I2 = 97% respectively. However, the result for the long-term death was highly heterogeneous. CONCLUSION: Since in-hospital and long-term MACEs and mortality were significantly higher following PCI in patients with versus without COPD, COPD should be considered a risk factor for the development of adverse clinical outcomes following PCI. However, the result for the long-term mortality was highly heterogeneous warranting further analysis.
Assuntos
Cardiopatias/terapia , Intervenção Coronária Percutânea/mortalidade , Doença Pulmonar Obstrutiva Crônica/mortalidade , Distribuição de Qui-Quadrado , Cardiopatias/complicações , Cardiopatias/diagnóstico , Cardiopatias/mortalidade , Mortalidade Hospitalar , Humanos , Razão de Chances , Intervenção Coronária Percutânea/efeitos adversos , Doença Pulmonar Obstrutiva Crônica/complicações , Doença Pulmonar Obstrutiva Crônica/diagnóstico , Medição de Risco , Fatores de Risco , Fatores de Tempo , Resultado do TratamentoRESUMO
A 64-year-old female patient presented with acute cerebellar ataxia. After ruling out vascular, infectious, metastatic, demyelinating, and medication etiologies, a paraneoplastic origin for her illness was determined. A renal mass was discovered and found to be renal cell carcinoma. Her symptoms resolved after a radical nephrectomy. Physicians should consider the diagnosis of paraneoplastic neurologic syndromes whenever a thorough evaluation fails to explain neurologic abnormalities.
Assuntos
Carcinoma de Células Renais/complicações , Ataxia Cerebelar/etiologia , Neoplasias Renais/complicações , Degeneração Paraneoplásica Cerebelar/etiologia , Carcinoma de Células Renais/diagnóstico por imagem , Carcinoma de Células Renais/imunologia , Feminino , Humanos , Neoplasias Renais/diagnóstico por imagem , Neoplasias Renais/imunologia , Pessoa de Meia-Idade , Degeneração Paraneoplásica Cerebelar/imunologia , Tomografia Computadorizada por Raios XAssuntos
Neoplasias do Colo/complicações , Doenças Linfáticas/diagnóstico por imagem , Sarcoidose/complicações , Adenocarcinoma/complicações , Adenocarcinoma/tratamento farmacológico , Adenocarcinoma/secundário , Quimioterapia Adjuvante , Neoplasias do Colo/tratamento farmacológico , Neoplasias do Colo/patologia , Feminino , Humanos , Doenças Linfáticas/etiologia , Metástase Linfática/diagnóstico por imagem , Doenças do Mediastino/diagnóstico por imagem , Doenças do Mediastino/etiologia , Pessoa de Meia-Idade , Tomografia por Emissão de Pósitrons , Sarcoidose/induzido quimicamente , Sarcoidose/diagnóstico por imagemRESUMO
Angiomyolipoma (AML) is a rare benign neoplasm that usually arises in the kidneys, but may rarely originate in sites such as the retroperitoneum, liver and bone. It is characterised by an intimate admixture of blood vessels, smooth muscle and fat. This multiphasic composition allows for its recognition on ultrasound and CT scan examination. Metastases are exceedingly uncommon, and only one other case of metastatic extrarenal AML exists in the literature. Histological variants of AML such as epithelioid angiomyolipoma (EAML) are considered to be locally aggressive. A unique case of an EAML of the retroperitoneum that metastasised to the liver and bone in an 80-year-old woman is described.
Assuntos
Angiomiolipoma/patologia , Neoplasias Hepáticas/secundário , Neoplasias Retroperitoneais/patologia , Idoso de 80 Anos ou mais , Angiomiolipoma/diagnóstico , Neoplasias Ósseas/diagnóstico , Neoplasias Ósseas/patologia , Neoplasias Ósseas/secundário , Feminino , Humanos , Neoplasias Hepáticas/diagnóstico , Neoplasias Hepáticas/patologiaAssuntos
Fístula Biliar/complicações , Doenças da Vesícula Biliar/complicações , Cálculos Biliares/complicações , Fístula Intestinal/complicações , Obstrução Intestinal/etiologia , Doenças do Colo Sigmoide/complicações , Idoso de 80 Anos ou mais , Fístula Biliar/diagnóstico , Diagnóstico Diferencial , Feminino , Doenças da Vesícula Biliar/diagnóstico , Humanos , Fístula Intestinal/diagnóstico , Obstrução Intestinal/diagnóstico , Doenças do Colo Sigmoide/diagnósticoRESUMO
T-cell large granular lymphocyte leukemia (T-LGL) also known as T-cell chronic lymphocytic leukemia is rare and comprises a small minority of all small lymphocytic leukemias. The concomitant presentation of T-LGL with acute myeloid leukemia (AML) has not been previously reported. We present an elderly gentleman with concomitant T-LGL and AML (non-M3) diagnosed by a combination of morphologic evaluation, immunophenotyping by flow cytometry, and T-cell gene rearrangement studies. The patient was managed with combination AML chemotherapy. He remains alive and well seven months after initial diagnosis. A brief review of literature is also presented.
Assuntos
Leucemia Mieloide/diagnóstico , Leucemia Prolinfocítica de Células T/diagnóstico , Doença Aguda , Idoso de 80 Anos ou mais , Antígenos CD/análise , Citometria de Fluxo , Humanos , Leucemia Mieloide/complicações , MasculinoAssuntos
Diarreia/fisiopatologia , Helmintos/isolamento & purificação , Animais , Feminino , HumanosAssuntos
Proteínas de Transporte/genética , Pólipos do Colo/genética , Proteínas de Ligação a DNA/genética , Proteínas Nucleares/genética , Polimorfismo Genético , Fumar/efeitos adversos , Proteínas Adaptadoras de Transdução de Sinal , Adulto , Idoso , Pareamento Incorreto de Bases , Proteínas de Transporte/metabolismo , Pólipos do Colo/enzimologia , Reparo do DNA , Proteínas de Ligação a DNA/metabolismo , Feminino , Predisposição Genética para Doença , Genótipo , Haplótipos , Humanos , Masculino , Pessoa de Meia-Idade , Proteína 1 Homóloga a MutL , Proteínas Nucleares/metabolismo , Fenótipo , Fatores de RiscoRESUMO
Pulmonary hypertension and cor pulmonale due to tumor emboli causing pulmonary tumor thrombotic microangiopathy (PTTM) is rare and extremely difficult diagnosis to make prior to death. Pulmonary hypertension due to metastatic tumor emboli should be included in the differential diagnosis of various causes of dyspnea in patients with a history of cancer or more common causes, including infection, thromboembolism, metastasis, adverse effects of drugs, and recurrent effusions. We describe a patient with gallbladder carcinoma who presented with progressive dyspnea and severe pulmonary hypertension. The etiology was tumor emboli and PTTM from gallbladder carcinoma, which remained elusive prior to her death despite appropriate clinical investigations and was established on autopsy. To the best of our knowledge, this is likely the second reported case of PTTM from metastatic gallbladder carcinoma.
Assuntos
Carcinoma de Células em Anel de Sinete/patologia , Neoplasias da Vesícula Biliar/patologia , Hipertensão Pulmonar/etiologia , Neoplasias Pulmonares/complicações , Pulmão/irrigação sanguínea , Embolia Pulmonar/etiologia , Trombose/etiologia , Dispneia/etiologia , Evolução Fatal , Feminino , Humanos , Pulmão/patologia , Neoplasias Pulmonares/patologia , Neoplasias Pulmonares/secundário , Microcirculação/patologia , Pessoa de Meia-Idade , Embolia Pulmonar/patologia , Trombose/patologiaAssuntos
Dispneia/etiologia , Insuficiência Cardíaca/diagnóstico , Peptídeo Natriurético Encefálico/sangue , Embolia Pulmonar/diagnóstico , Idoso , Idoso de 80 Anos ou mais , Biomarcadores/sangue , Diagnóstico Diferencial , Erros de Diagnóstico/prevenção & controle , Eletrocardiografia , Feminino , Insuficiência Cardíaca/complicações , Humanos , Embolia Pulmonar/complicaçõesAssuntos
Antineoplásicos/uso terapêutico , Finasterida/uso terapêutico , Hiperplasia Prostática/tratamento farmacológico , Neoplasias da Próstata/diagnóstico , Humanos , Masculino , Antígeno Prostático Específico/sangue , Antígeno Prostático Específico/efeitos dos fármacos , Neoplasias da Próstata/prevenção & controle , Ensaios Clínicos Controlados Aleatórios como AssuntoAssuntos
Antineoplásicos/efeitos adversos , Neoplasias Brônquicas/etiologia , Carcinoma de Célula de Merkel/complicações , Linfoma de Células B/etiologia , Radioterapia/efeitos adversos , Idoso , Carcinoma de Célula de Merkel/tratamento farmacológico , Carcinoma de Célula de Merkel/radioterapia , Feminino , Neoplasias de Cabeça e Pescoço/complicações , Neoplasias de Cabeça e Pescoço/tratamento farmacológico , Neoplasias de Cabeça e Pescoço/radioterapia , Humanos , Segunda Neoplasia Primária/etiologiaAssuntos
Abscesso/etiologia , Doenças Mamárias/etiologia , Neoplasias da Mama/complicações , Carcinoma de Células Escamosas/complicações , Adulto , Neoplasias da Mama/diagnóstico , Neoplasias da Mama/terapia , Carcinoma de Células Escamosas/diagnóstico , Carcinoma de Células Escamosas/terapia , Feminino , HumanosRESUMO
Nocardia farcinica is an uncommon cause of nocardiosis and usually infects immunocompromised individuals. We describe a patient with Hodgkin's disease and a thigh abscess due to N. farcinica. To the best of our knowledge, this has never been reported before in the English literature. It is important to recognize this complication, because a delay in diagnosis may result in widespread dissemination. Unless initially suspected, culture and identification will be delayed, as selective media for isolating Nocardia are not routinely used in most clinical laboratories. It is also important to differentiate N. farcinica from other Nocardia species due to its resistance to many antibiotics that are routinely used to treat abscesses, including cephalosporins. A case report along with literature review is presented in an effort to stress the importance of including this pathogen in the differential diagnosis of immunocompromised patients with abscesses.