[Herpetic infection of spermatozoa in failure of reproductive technologies and spontaneous abortion].

Herpes simplex virus (HSV) was studied in ejaculate of 36 men whose wives had the history of spontaneous abortions, or failure of artificial insemination (AI), or extracorporeal fertilization (ECF). The control group consisted of 222 patients examined prophylactically after urogenital inflammation or for primary infertility. HSV was detected with immunofluorescence (IF) reaction with monoclonal antibodies to HSV antigens, rapid culture method (RCM) and transmission electronic microscopy. HSV antigens were detected in fraction of mobile spermatozoa in 13 (65%) of 20 samples from patients of the study group. HSV detectability in the study group was significantly higher than in the controls (p = 0.003). Intragametic capsides of HSV were detected at ultrastructural investigation in 13 of 19 (68%) ejaculate samples from patients of the study group in whom IF and/ or RCM results were positive. The study of 6 ejaculate samples of this group in which HSV was not detected by IF or RCM and 24 control samples HSV capsides were not detected. The following conclusions can be made: mobile spermatozoa of normal morphology can be infected with HSV; as shown morphologically, samples of ejaculate from men whose wives had spontaneous abortions contained intragametic HSV capsides; intragametic HSV infection of spermatozoa had a negative effect on the course of pregnancy and/or embryon vitality.

[Drainage of the uterine cavity in postpartum endometritis]. / Drenirovanie polosti matki pri poslerodovom éndometrite.

Analyzes the results of management of protracted torpid postpartum endometritis (10 cases) and severe septic endometritis following a cesarean section (9 cases), multiple-modality treatment of these patients including prolonged influent-aspiration drainage of the uterine cavity. Describes the drainage system, its fixation, and operation. Discusses a differentiated approach to infusion of the drugs directly into the uterine cavity in cases with the uterine inflammations. Demonstrates the advantages of multiple-modality treatment including the above method for some forms of postpartum endometritis.