[Causes of death from tuberculosis in children under the present-day conditions].

Analysis of the causes of death from tuberculosis in 15 children in one of the central regions of Russia has indicated that in the past 14 years, the territorial childhood mortality rates have been 0.10-0.20 per 100,000 children. The main cause of death is tuberculous meningoencephalitis (n = 10); caseous pneumonia (n = 3), and generalized tuberculosis with severe concomitant diseases (n = 2) were less common. Tuberculous meningoencephalitis was postmortally diagnosed in 4 children who had received intensive nonspecific therapy using large doses of corticosteroid hormones. This led to the development of severe pyonecrotic meningoencephalitis with great brain edema and hemorrhoidal portions, which was early known as steroid-induced tuberculosis.

[Tuberculin sensitivity in infants and preschool children]. / Tuberkulinovaia chuvstvitel'nost' u detei rannego i doshkol'nogo vozrasta.

Marked fluctuations in sensitivity to tuberculin related to the time of nonspecific vaccinations were found in children aged 1 to 7 years vaccinated with BCG within the first week of life in annual Mantoux test (2 tuberculin units). At the age of 3 and 7 years vaccinations raise sensitivity to tuberculin causing a rise in positive reactions to tuberculin. This indicates changes in postvaccination allergy to BCG.

[Organization of care for tuberculosis children who had contact with maternal hospital worker suffering from bacillar tuberculosis]. / Organizatsiia protivotuberkuleznoi pomoshchi detiam, imevshim kontakt v rodil'nom dome s sotrudnikom, bol'nym batsilliarnym tuberkulezom.

While contacting a patient with bacillar tuberculosis, neonates and their mother are at risk for the disease, which makes it necessary to make up a programme that involves emergency antituberculosis measures. Among them primary specific drug therapy in all children in contacts, which may prevent tuberculosis in them, is highly effective.