[Solitary extramedullary plasmocytoma of tubaric tonsil]. / Plasmocitoma solitario extramedular de amígdala tubárica.

Several histopathological modalities of tumours can grow in the rhinopharynx. Solitary extramedullary plasmocytoma (SEP) is a low frequent variety of low-grade lymphoma. The aim of this work is to present a new case of SEP localized in rhinopharynx and to perform a review of diagnostic and therapeutic protocols of these neoplasias. They must be taken into account in the differential diagnosis of nasopharyngeal tumours.

Plasmocitoma solitario extramedular de amígdala tubárica / Solitary extramedullary plasmocytoma of tubaric tonsil

La nasofaringe es el asiento de tumores de muy variada naturaleza. El plasmocitoma solitario extramedular (PSE) es una variante poco frecuente de linfoma de bajo grado, cuya localización a este nivel es muy rara. El objetivo de este trabajo es presentar un nuevo caso de PSE localizado a nivel de la amígdala tubárica y revisar los protocolos diagnósticos y terapéuticos de este tipo infrecuente de neoplasias que deben tenerse en cuenta en el diagnóstico diferencial de los tumores de nasofaringe (AU)

Several histopathological modalities of tumours can grow in the rhinopharynx. Solitary extramedullary plasmocytoma (SEP) is a low frequent variety of low-grade lymphoma. The aim of this work is to present a new case of SEP localized in rhinopharynx and to perform a review of diagnostic and therapeutic protocols of these neoplasias. They must be taken into account in the differential diagnosis of nasopharyngeal tumours (AU)

Solitary fibrous tumor of the thigh with epithelioid features: a case report.

BACKGROUND: Extrapleural Solitary Fibrous tumors (SFTs) have been increasingly reported. The retroperitoneum, deep soft tissues of proximal extremities, abdominal cavity, trunk, head and neck are the most common extraserosal locations reported. Microscopically they show a wide range of morphological features, and so the differential diagnosis is extensive. Immunohistochemically, they commonly express CD34, vimentin, bcl-2 and CD99. Epithelial membrane antigen (EMA) and smooth muscle actin (SMA) may occasionally be expressed. Epithelioid morphology in extrapleural SFT has only very occasionally been described (five cases reported), some of them with biphasic pattern and others with malignant characteristics. CASE PRESENTATION: A SFT of the thigh with epithelioid areas in a 63 year old woman is reported. Microscopically the tumor showed areas hypo and hipercellular. At the periphery of the hipercellular areas there were nodules composed of epithelioid cells. Immunohistochemically both the spindle and epithelioid cells were positive for CD34, vimentin, bcl-2 and CD99. Epithelial, neural and muscular markers were negative. Molecular study was done and ruled out a synovial sarcoma. CONCLUSION: Ten cases of SFT of the thigh have been reported but to our knowledge this is the first case with epithelioid morphology affecting the extremities. Identification of this pattern of SFT is of importance, to avoid misdiagnosis with other more aggressive conditions in soft tissue.