RESUMO
Intradiploic meningioma, which may be classified as a subgroup of intraosseous meningioma, is a rarely encountered disorder. To date, less than 10 cases have been reported. Here, we report a case of fronto-orbitonasal intradiploic meningioma. A 12-year-old female with exophthalmos and diplopia was operated on for a cranial intradiploic mass lesion. Histopathological evaluation of the specimen confirmed the diagnosis of intradiploic psammomatous meningioma. Her exophthalmos did not change, but the diplopia disappeared. This case is unique in that it is an extensive case of intradiploic meningioma of the orbital roof and frontal base in a child. Intradiploic meningiomas generally are of psammomatous type. Especially tumors adjacent to the orbita cause exophthalmos; cases located on the other side of the calvarium may not cause any symptom or sign other than headache or sometimes a mass on the scalp. Treatment, as with meningiomas located in the intracranial cavity, is total resection of the lesion.
Assuntos
Osso Frontal , Meningioma/diagnóstico , Neoplasias Nasais/diagnóstico , Neoplasias Orbitárias/diagnóstico , Neoplasias Cranianas/diagnóstico , Biópsia , Criança , Diplopia/etiologia , Exoftalmia/etiologia , Feminino , Humanos , Meningioma/complicações , Meningioma/cirurgia , Neoplasias Nasais/complicações , Neoplasias Nasais/cirurgia , Neoplasias Orbitárias/complicações , Neoplasias Orbitárias/cirurgia , Neoplasias Cranianas/complicações , Neoplasias Cranianas/cirurgia , Tomografia Computadorizada por Raios X , Resultado do TratamentoRESUMO
21 patients with gunshot wounds were retrospectively evaluated. They were 19 male and 2 female, age range was 9-24. All of the patients underwent a plain x-ray and computed tomography evaluation. 9 patients had intracerebral hematoma, 4 had subdural hematoma, 1 had epidural hematoma and 1 had intraventricular hematoma. 9 patients were observed to have bullet in the cranium. All the patients with glasgow coma scale 3-5 at the admittance died. 15 patients underwent surgical treatment. 3 patients had cerebrospinal fluid fistula postoperatively and underwent reoperation. Extensivity of the lacerated brain, localization of the lesion and the glasgow coma scale at the admittance affect the outcome in gunshot wounds.
Assuntos
Tratamento de Emergência/estatística & dados numéricos , Traumatismos Cranianos Penetrantes/epidemiologia , Traumatismos Cranianos Penetrantes/cirurgia , Ferimentos por Arma de Fogo/epidemiologia , Ferimentos por Arma de Fogo/cirurgia , Adolescente , Adulto , Criança , Feminino , Escala de Coma de Glasgow , Traumatismos Cranianos Penetrantes/complicações , Traumatismos Cranianos Penetrantes/diagnóstico por imagem , Humanos , Hemorragia Intracraniana Traumática/complicações , Hemorragia Intracraniana Traumática/diagnóstico por imagem , Hemorragia Intracraniana Traumática/epidemiologia , Hemorragia Intracraniana Traumática/cirurgia , Masculino , Complicações Pós-Operatórias/epidemiologia , Tomografia Computadorizada por Raios X , Turquia/epidemiologia , Ferimentos por Arma de Fogo/diagnóstico por imagemAssuntos
Abscesso/microbiologia , Encefalopatias/complicações , Brucelose/complicações , Doenças da Hipófise/microbiologia , Abscesso/cirurgia , Adulto , Anti-Infecciosos/uso terapêutico , Encefalopatias/tratamento farmacológico , Brucelose/tratamento farmacológico , Quimioterapia Combinada , Endoscopia , Feminino , Humanos , Doenças da Hipófise/cirurgia , Rifampina/uso terapêutico , Sulfametoxazol/uso terapêutico , Trimetoprima/uso terapêuticoAssuntos
Acetato de Medroxiprogesterona/uso terapêutico , Distúrbios Menstruais/tratamento farmacológico , Doenças do Sistema Nervoso/tratamento farmacológico , Doenças do Sistema Nervoso Periférico/tratamento farmacológico , Congêneres da Progesterona/uso terapêutico , Raízes Nervosas Espinhais , Adulto , Feminino , HumanosAssuntos
Vértebras Cervicais , Hematoma/cirurgia , Paraplegia/reabilitação , Doenças da Coluna Vertebral/cirurgia , Vértebras Cervicais/diagnóstico por imagem , Criança , Espaço Epidural , Hematoma/complicações , Humanos , Masculino , Paraplegia/etiologia , Período Pós-Operatório , Radiografia , Doenças da Coluna Vertebral/complicaçõesRESUMO
This study was designed to analyze the effect of early indomethacin on the lipid peroxidation after spinal cord injury in rats. The use of anti-inflammatory drugs to affect delayed and secondary injury after trauma to the spinal cord has now become a matter of standard clinical practice. However, spinal cord injury remains an enormous clinical problem and research that may lead to improved treatment is to be encouraged and commended. Three experimental groups consisting of 40 rats each were formed. Using microsurgical technique, total laminectomy between T5 and T10 was performed. Spinal cord injury was achieved with an epidural aneurysm clip, and pharmacological treatment immediate after the injury was performed by injecting indomethacin intraperitoneally (i.p.) at a dose of 3 mg/kg to indomethacin-treated group. The three main groups were divided into subgroups of 8 rats each. It was planned to stop the biochemical reactions at a different time in each of these subgroups, by the application of liquid nitrogen to the spinal cord and paravertebral structures at the end of the 1st, 15th, 30th, 60th, and 90th minutes. All the spinal cords were removed and protected from further reactions by immersing in the liquid nitrogen tank. The lipid peroxidation levels were assessed by determining thiobarbituric acid reactive substances formation. The results of the study showed that the administration of 3 mg/kg indomethacin immediately after spinal cord injury induces lipid peroxidation to a significant degree (p<0.05 one-way ANOVA and Tukey HSD tests) when compared to the saline-treated group. This result suggests that early posttraumatic indomethacin treatment may be harmful in spinal cord injury.
Assuntos
Anti-Inflamatórios não Esteroides/toxicidade , Indometacina/toxicidade , Traumatismos da Medula Espinal/patologia , Animais , Feminino , Injeções Intraperitoneais , Peroxidação de Lipídeos/efeitos dos fármacos , Ratos , Ratos Wistar , Medula Espinal/efeitos dos fármacos , Medula Espinal/patologiaRESUMO
Multiple hydatid cysts of the brain are uncommon and may be either primary or secondary. We report a 12-year-old child with multiple hydatid cysts of the brain occurring 1 year after surgical rupture of a primary large and infected cerebral hydatid cyst. Surgical removal of hydatid cysts was successfully performed. Albendazole (10 mg/kg twice daily for 12 weeks) was administered to the patient in the postoperative stage.