1.
Biol Sci Space
; 12(3): 320-1, 1998 Nov.
Artigo
em Japonês
| MEDLINE
| ID: mdl-12512548
2.
J Exp Med
; 159(2): 617-22, 1984 Feb 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-6420503
RESUMO
The frequency of lambda light chain (L) producing cells in immunoglobulin-producing cells that have been generated in vitro from bone marrow pre-B cells was investigated. The frequency of lambda-producing cells obtained in such a culture was three- to eightfold higher than that observed in the culture of mature spleen B cells. These results suggest that the activation of lambda gene at pre-B cell stage occurs far more frequently than the frequency presumed from the percentage of lambda-bearing cells in mature B cells.