1.
J Org Chem
; 86(21): 14777-14785, 2021 11 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34609859
RESUMO
Based on sequential organic transformations, that is, diimine formation, Staudinger [2 + 2] ketene-imine cycloaddition, and ring-closing metathesis (RCM) reactions, the synthesis with full structural identification including NMR and HRMS spectral data along with single X-ray diffraction analysis (for anti 7b, anti 8b, syn 9a, and anti 9b) of the first syn/anti bis-4-spiro-ß-lactams-based azacrown ethers (7a,b-9a,b) is reported.