Treatment of an adult case with Japanese encephalitis / 中华实验和临床病毒学杂志

Objective@#The features of clinical, laboratory and radiologic examinations of an adult patient with Japanese encephalitis (JE) were analyzed to understand the differences in clinical characteristics between adult and children patients, and to investigate the method of etiological tests.@*Methods@#The clinical, laboratory tests and radiographic data of an adult case with JE requiring hospitalization were analyzed retrospectively and the related literature was reviewed.@*Results@#The clinical presentation of patients with JE was nonspecific, the patient presented with fever, consciousness and cognitive impairment, convulsion and meningeal irritation. Its main test indicator is IgM antibody of Japanese encephalitis virus(JEV) in acute cerebrospinal fluid and serum specimens.Craniocerebral MRI is an important auxiliary examination for JE, the common sites involved are thalamus, basal ganglia and cerebral cortex, of which thalamus is almost 100% affected.@*Conclusions@#The clinical presentation of patients with JE was nonspecific. Clear diagnosis should be accompanied by the combination of epidemiology, laboratory tests and specific antibodies detection. Neural damages commonly occur in thalamus.

MRI features of Rosai-Dorfman disease in CNS / 实用放射学杂志

Objective To summarize the clinical and imaging characteristics of primary Rosai-Dorfman disease (RDD)in central nervous system in order to understand well its features and improve the diagnosis.Methods The clinical and imaging features in 3 patients with RDD in CNS proved by pathology were retrospectively analyzed in combination with the related literatures.Results The lesions in 2 patients occurred in brain and other lesion in 1 occurred outside the brain.Iso-or slight hyperintensity on T1 WI and marked enhancement of the lesion were found.Single lesion was found in 2 patients near the dura mater and located near the superior sagittal sinus or cervical spinal cord.Multiple lesions in 1 patient were located in the lateral ventricle.Conclusion It’s suggested that single or multiple lesions in dural or spinal meninges located in the midline or near the intracephalic venous system would be considered as RDD in CNS.