RESUMO
A 57-year-old woman was hospitalized with malignant lymphoma of the right talus. After treatment, complete remission was obtained. Gallium-67 scintigraphy to confirm the remission demonstrated increased uptake in the whole body skeletal muscle, especially in her thighs. Biopsy of right gastrocnemius muscle showed epithelioid granuloma. Serum angiotensin-converting enzyme activity (ACE) and lysozyme had increased to several times the normal range. We diagnosed her disease as bone-associated sarcoidosis-lymphoma syndrome. Human herpes virus 8 (HHV-8) genome was examined in the bone marrow specimen, and the relationship between sarcoidosis-lymphoma syndrome and HHV-8 was discussed.
Assuntos
Neoplasias Ósseas/etiologia , Linfoma/etiologia , Sarcoidose/complicações , Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico , Medula Óssea/virologia , Neoplasias Ósseas/diagnóstico , Neoplasias Ósseas/tratamento farmacológico , Neoplasias Ósseas/patologia , Ciclofosfamida/uso terapêutico , Doxorrubicina/uso terapêutico , Feminino , Radioisótopos de Gálio , Herpesvirus Humano 8/isolamento & purificação , Humanos , Linfoma/diagnóstico , Linfoma/tratamento farmacológico , Linfoma/patologia , Pessoa de Meia-Idade , Prednisona/uso terapêutico , Radiografia , Cintilografia , Síndrome , Tálus/diagnóstico por imagem , Vincristina/uso terapêuticoAssuntos
Doenças dos Trabalhadores Agrícolas/etiologia , Frutas , Pólen/imunologia , Rinite Alérgica Sazonal/etiologia , Adolescente , Adulto , Doenças dos Trabalhadores Agrícolas/terapia , Criança , Dessensibilização Imunológica , Feminino , Humanos , Imunoglobulina E/análise , Masculino , Pessoa de Meia-Idade , Rinite Alérgica Sazonal/terapiaRESUMO
In order to examine effects of PSK (polysaccharide Kureha) on laryngeal cancer, clinical results of 28 patients treated by PSK were compared with those of 31 of the historical control group. Three months after treatments, the PSK group showed a higher cumulative survival rate and better results in immunological parameters such as counts of peripheral lymphocyte, PPD and PHA skin reaction. However, these differences between the PSK group and the control group were not significant statistically, except peripheral leucocyte counts. The side effect was found in one patient who complained of stomach discomfort after applicating PSK.
