Association Between Childhood Exposure to Pet Cats and Later Diagnosis of Schizophrenia: A Case-Control Study in Saudi Arabia.

There is an increasing number of reports suggesting an effect of adverse environmental factors during vulnerable periods of prenatal and perinatal development in the etiology of schizophrenia. Cat-transmitted infections, especially Toxoplasma gondii, are possible risk factors for the later development of schizophrenia. We conducted a case-control study to examine childhood cat ownership in 78 patients with schizophrenia (cases), 78 outpatients with depression and anxiety disorders (control group one), and 78 outpatients with no psychiatric history (control group two). Cat ownership before the age of 13 was reported by 52.6%, 44.9%, and 24.4% of patients in cases, control group one, and control group two, respectively. Compared with non-psychiatric patients, patients with schizophrenia were 3.4 times more likely to report owning cats in their childhood (odds ratio (OR)=3.441; p=0.000; 95% confidence interval (CI)=1.740-6.804). Compared with both control groups, the likelihood of owning a cat as a child was 2.1 times more among cases (OR=2.093; p=0.008; 95% CI=1.203-3.640). Age, female gender, and family history appeared to be positively associated with cat ownership and schizophrenia. This study supports the evidence of a relationship between childhood exposure to pet cats and the later development of schizophrenia. Further in-depth research is needed to clarify the relationship between exposure to pet cats in childhood and later diagnosis of schizophrenia, adjusting for potential confounders.

Prevalence and Associated Factors of Depression among Patients with Diabetes at Jazan Province, Saudi Arabia: A Cross-Sectional Study.

CONTEXT: Patients with diabetes mellitus (DM) have a poorer quality of life when compared with patients without DM. In fact, one in every five diabetic patients suffers from comorbid depression, which can lead to poor management, poor compliance with treatment, and low quality of life. Therefore, we assessed the prevalence of depression and identified its associated factors among diabetic patients at Jazan Province, KSA. METHODS AND MATERIALS: A cross-sectional study was conducted among 500 diabetic patients attending a diabetic center in addition to four primary healthcare centers. We used a simple Arabic translation of the Beck Depression Inventory (BDI II) tool to evaluate the depression level among the subjects. We also evaluated the frequencies of certain sociodemographic characteristics and clinical information. Moreover, we performed univariate and multivariate analyses to identify the potential risk factors using adjusted odds ratios (AORs). RESULTS: The prevalence of depression among DM patients was 20.6%. The majority of patients showed no depression (N = 285, 59.4%), one-fifth had mild depression (N = 96, 20.0%), some (N = 55, 11.4%) had moderate depression, and some had severe depression (N = 44, 9.2%). Depression was significantly more prevalent among uneducated patients (N = 27, 31.8%) (X2 = 17.627, P = 0.001) and patients with low monthly income (< 2500 SR/month) (N = 33, 22.8%) (X2 = 9.920, P = 0.019). Hypertension (AOR = 2.531, 95% CI [1.454, 4.406]) and ischemic heart diseases (AOR = 3.892, 95% CI [1.995, 7.593]) were considered as risk factors for depression among diabetic patients. CONCLUSIONS: Almost one in every five patients with DM is affected by depression coexisting with cardiovascular diseases. Therefore, screening for psychological problems, proper treatment, and educating patients with diabetes about DM self-management should be routine components of DM care.

Mental Health Literacy Among Undergraduate Students of a Saudi Tertiary Institution: A Cross-sectional Study.

The issue of mental health literacy has been widely studied in developed countries, with few studies conducted in Arab countries. In this study we aimed to investigate mental health literacy and attitudes towards psychiatric patients among students of Jazan University, Kingdom of Saudi Arabia. A crosssectional study was conducted among undergraduate students using a validated Arabicversion questionnaire. A total of 557 students were recruited from different Jazan university colleges. The majority of students (90.3%) have intermediate mental health literacy. Regarding the etiology of mental illness, students agreed that genetic inheritance (45.8%), poor quality of life (65%) and social relationship weakness (73.1%) are the main causes of mental illness. The majority thought that mentally ill people are not capable of true friendships (52.5%) and that anyone can suffer from a mental illness (49.4%). Students' attitudes towards psychiatric patients were mixed, with 68.7% reporting that they could maintain a friendship with a mentally ill person and that people with mental illness should have the same rights as anyone else (82.5%). Mental health literacy among university students was intermediate. There is an urgent need for health educational programs to change the attitudes of students regarding this important health issue.