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Saudi J Kidney Dis Transpl ; 25(1): 58-65, 2014 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-24434383

RESUMO

Knowledge of the epidemiology and risk profile of peripheral vascular disease among patients with chronic kidney disease (CKD) has a potential role for determining its outcome. This study assessed the epidemiological aspects and risk factors of carotid artery stenosis (CAS), assessed by clinical ankle brachial index (ABI), in patients on dialysis. This study was performed on 84 patients with CKD undergoing hemodialysis (HD; n = 65) or peritoneal dialysis (PD; n = 19). The ABI was measured using a concurrent oscillometric method and Color Doppler sonography. An ABI value >0.9 was defined as normal. Severity of the stenosis was determined using B-Mode sonography. Overall, CAS was seen in 51.2% of the study patients. No significant difference was found in the overall prevalence of CAS between the HD and PD groups (50.8% vs. 52.6%, P = 0.552). The mean ABI in the HD and PD groups was 1.13 and 1.06, respectively. Among patient characteristics, advanced age was found to be a predictor of CAS in the study patients. Gender, type of dialysis or underlying risk factors could not predict CAS. ABI measurement was an acceptable predictor of CAS, with a receiver operator characteristic of 0.645. The optimal cut-off for ABI for predicting CAS was identified at 1.0; this yielded a sensitivity of 70.8% and a specificity of 63.6% for the test. In conclusion, a notable number of patients undergoing dialysis for CKD had CAS. The main predictive factor was advanced age. ABI measurement seems to be an acceptable tool to diagnose CAS.


Assuntos
Índice Tornozelo-Braço , Estenose das Carótidas/diagnóstico , Estenose das Carótidas/epidemiologia , Diálise Peritoneal , Diálise Renal , Insuficiência Renal Crônica/terapia , Adulto , Idoso , Índice Tornozelo-Braço/métodos , Distribuição de Qui-Quadrado , Feminino , Humanos , Irã (Geográfico)/epidemiologia , Modelos Logísticos , Masculino , Pessoa de Meia-Idade , Análise Multivariada , Razão de Chances , Oscilometria , Diálise Peritoneal/efeitos adversos , Valor Preditivo dos Testes , Prevalência , Curva ROC , Diálise Renal/efeitos adversos , Insuficiência Renal Crônica/diagnóstico , Insuficiência Renal Crônica/epidemiologia , Fatores de Risco , Índice de Gravidade de Doença , Ultrassonografia Doppler em Cores
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