1.
Org Biomol Chem
; 9(21): 7535-8, 2011 Nov 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21938297
RESUMO
Synthesis of substituted 1,3-dienes was achieved via gold(I)-catalyzed Claisen rearrangement of allenyl vinyl ethers. The N-heterocyclic carbene gold chloride catalyst (IPrAuCl) was superior in terms of activity and selectivity and afforded the 3,3-product in excellent yields. A proposed cation-π inter-action played a significant role in affecting the reaction rate.