Nucleolar organizer regions in breast cytology material.

OBJECTIVE: To evaluate the presence of nucleolar organizer regions (NORs) by the argyrophil NOR (AgNOR) technique on scrape cytology on breast lumps. STUDY DESIGN: The study group consisted of 112 breast lumps that were sent for frozen section and included fibrocystic disease (52 cases), fibroadenomas (15 cases) and carcinomas (45 cases). Scrape cytology was performed on each case, and the number of AgNOR dots was recorded for 50 cells and the mean value calculated. RESULTS: The mean AgNOR counts were statistically significantly higher in malignant lesions in comparison to either fibroadenomas or fibrocystic changes. CONCLUSION: The AgNOR technique could be of use in cytologic material as an adjunct to fine needle aspiration of breast lesions.

[The fat mobilization syndrome in guinea pigs (Cavia porcellus L.)]. / Untersuchungen zum Fettmobilisationssyndrom am Meerschweinchen (Cavia porcellus L.).

Feeding experiments were applied to 82 guinea pigs, different by age, sex, and stage of reproduction, and showed that high-energy feeding and subsequent feed withdrawal could trigger off with high probability a fat mobilising syndrome with clinically manifest ketosis in animals in gravidity and lactation or subclinical ketosis in all non-gravid individuals. High-energy or restrictive feeding alone did not cause in guinea pigs any disease along the lines of gravidity toxicosis. Aspects relating to aetiological and pathogenetic comparability with ruminants are discussed in some detail.