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J Theor Biol ; 433: 73-84, 2017 11 21.
Artigo em Inglês | MEDLINE | ID: mdl-28844907

RESUMO

Proper design of stent for application at specific aneurysm effect arteries could help to reduce the issues with thrombosis and aneurysm. In this paper, four types of stent configuration namely half-Y (6 mm), half-Y (4 mm), cross-bar, and full-Y configuration will implanted on real 3D artery bifurcation aneurysm effected arteries. Comparisons were then conducted based on the flow patterns after stent placement using both LBM-based solver and PIV experimental findings. According to the data obtained from all 4 stent designs, the flow profiles and the computed velocity from both methods were in agreement with each other. Both methods found that half-Y (6 mm) stent configuration is by far the best configuration in reducing the blood velocity at the vicinity of the aneurysm sac. The analysis also show that the half-Y (6 mm) stent configuration recorded the highest percentage of velocity reduction and managed to substantially reduce the pressure at the bifurcation region. This high flow velocity reduction through the use of half-Y stent could consequently promote the formation of thrombus thereby reducing the risk of rupture in the aneurysm sac.


Assuntos
Aneurisma/terapia , Desenho de Equipamento/métodos , Stents/normas , Velocidade do Fluxo Sanguíneo , Prótese Vascular , Simulação por Computador , Humanos , Modelos Cardiovasculares , Reologia
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