Hybrid Diagnosis Models for Autism Patients Based on Medical and Sociodemographic Features Using Machine Learning and Multicriteria Decision-Making (MCDM) Techniques: An Evaluation and Benchmarking Framework.

Method: The three-phase framework integrated the MCDM and ML to develop the diagnosis models and evaluate and benchmark the best. Firstly, the new ASD-dataset-combined medical tests and sociodemographic characteristic features is identified and preprocessed. Secondly, developing the hybrid diagnosis models using the intersection process between three FS techniques and five ML algorithms introduces 15 models. The selected medical tests and sociodemographic features from each FS technique are weighted before feeding the five ML algorithms using the fuzzy-weighted zero-inconsistency (FWZIC) method based on four psychiatry experts. Thirdly, (i) formulate a dynamic decision matrix for all developed models based on seven evaluation metrics, including classification accuracy, precision, F1 score, recall, test time, train time, and AUC. (ii) The fuzzy decision by opinion score method (FDOSM) is used to evaluate and benchmark the 15 models concerning the seven evaluation metrics. Results: Results reveal that (i) the three FS techniques have obtained a size different from the others in the number of the selected features; the sets were 39, 38, and 41 out of 48 features. Each set has its weights constructed by FWIZC. Considered sociodemographic features have been mostly selected more than medical tests within FS techniques. (ii) The first three best hybrid models were "ReF-decision tree," "IG-decision tree," and "Chi2-decision tree," with score values 0.15714, 0.17539, and 0.29444. The best diagnosis model (ReF-decision tree) has obtained 0.4190, 0.0030, 0.9946, 0.9902, 0.9902, 0.9902, 0.9902, and 0.9951 for the C1=train time, C2=test time, C3=AUC, C4=CA, C5=F1 score, C6=precision, and C7=recall, respectively. The developed framework would be beneficial in advancing, accelerating, and selecting diagnosis tools in therapy with ASD. The selected model can identify severity as light, medium, or intense based on medical tests and sociodemographic weighted features.

Diagnosis-Based Hybridization of Multimedical Tests and Sociodemographic Characteristics of Autism Spectrum Disorder Using Artificial Intelligence and Machine Learning Techniques: A Systematic Review.

Autism spectrum disorder (ASD) is a complex neurobehavioral condition that begins in childhood and continues throughout life, affecting communication and verbal and behavioral skills. It is challenging to discover autism in the early stages of life, which prompted researchers to intensify efforts to reach the best solutions to treat this challenge by introducing artificial intelligence (AI) techniques and machine learning (ML) algorithms, which played an essential role in greatly assisting the medical and healthcare staff and trying to obtain the highest predictive results for autism spectrum disorder. This study is aimed at systematically reviewing the literature related to the criteria, including multimedical tests and sociodemographic characteristics in AI techniques and ML contributions. Accordingly, this study checked the Web of Science (WoS), Science Direct (SD), IEEE Xplore digital library, and Scopus databases. A set of 944 articles from 2017 to 2021 is collected to reveal a clear picture and better understand all the academic literature through a definitive collection of 40 articles based on our inclusion and exclusion criteria. The selected articles were divided based on similarity, objective, and aim evidence across studies. They are divided into two main categories: the first category is "diagnosis of ASD based on questionnaires and sociodemographic features" (n = 39). This category contains a subsection that consists of three categories: (a) early diagnosis of ASD towards analysis, (b) diagnosis of ASD towards prediction, and (c) diagnosis of ASD based on resampling techniques. The second category consists of "diagnosis ASD based on medical and family characteristic features" (n = 1). This multidisciplinary systematic review revealed the taxonomy, motivations, recommendations, and challenges of diagnosis ASD research in utilizing AI techniques and ML algorithms that need synergistic attention. Thus, this systematic review performs a comprehensive science mapping analysis and identifies the open issues that help accomplish the recommended solution of diagnosis ASD research. Finally, this study critically reviews the literature and attempts to address the diagnosis ASD research gaps in knowledge and highlights the available ASD datasets, AI techniques and ML algorithms, and the feature selection methods that have been collected from the final set of articles.

Triage and priority-based healthcare diagnosis using artificial intelligence for autism spectrum disorder and gene contribution: A systematic review.

The exact nature, harmful effects and aetiology of autism spectrum disorder (ASD) have caused widespread confusion. Artificial intelligence (AI) science helps solve challenging diagnostic problems in the medical field through extensive experiments. Disease severity is closely related to triage decisions and prioritisation contexts in medicine because both have been widely used to diagnose various diseases via AI, machine learning and automated decision-making techniques. Recently, taking advantage of high-performance AI algorithms has achieved accessible success in diagnosing and predicting risks from clinical and biological data. In contrast, less progress has been made with ASD because of obscure reasons. According to academic literature, ASD diagnosis works from a specific perspective, and much of the confusion arises from the fact that how AI techniques are currently integrated with the diagnosis of ASD concerning the triage and priority strategies and gene contributions. To this end, this study sought to describe a systematic review of the literature to assess the respective AI methods using the available datasets, highlight the tools and strategies used for diagnosing ASD and investigate how AI trends contribute in distinguishing triage and priority for ASD and gene contributions. Accordingly, this study checked the Science Direct, IEEE Xplore Digital Library, Web of Science (WoS), PubMed, and Scopus databases. A set of 363 articles from 2017 to 2022 is collected to reveal a clear picture and a better understanding of all the academic literature through a final set of 18 articles. The retrieved articles were filtered according to the defined inclusion and exclusion criteria and classified into three categories. The first category includes 'Triage patients based on diagnosis methods' which accounts for 16.66% (n = 3/18). The second category includes 'Prioritisation for Risky Genes' which accounts for 66.6% (n = 12/18) and is classified into two subcategories: 'Mutations observation based', 'Biomarkers and toxic chemical observations'. The third category includes 'E-triage using telehealth' which accounts for 16.66% (n = 3/18). This multidisciplinary systematic review revealed the taxonomy, motivations, recommendations and challenges of ASD research that need synergistic attention. Thus, this systematic review performs a comprehensive science mapping analysis and discusses the open issues that help perform and improve the recommended solution of ASD research direction. In addition, this study critically reviews the literature and attempts to address the current research gaps in knowledge and highlights weaknesses that require further research. Finally, a new developed methodology has been suggested as future work for triaging and prioritising ASD patients according to their severity levels by using decision-making techniques.

Telehealth utilization during the Covid-19 pandemic: A systematic review.

During the coronavirus disease (COVID-19) pandemic, different technologies, including telehealth, are maximised to mitigate the risks and consequences of the disease. Telehealth has been widely utilised because of its usability and safety in providing healthcare services during the COVID-19 pandemic. However, a systematic literature review which provides extensive evidence on the impact of COVID-19 through telehealth and which covers multiple directions in a large-scale research remains lacking. This study aims to review telehealth literature comprehensively since the pandemic started. It also aims to map the research landscape into a coherent taxonomy and characterise this emerging field in terms of motivations, open challenges and recommendations. Articles related to telehealth during the COVID-19 pandemic were systematically searched in the WOS, IEEE, Science Direct, Springer and Scopus databases. The final set included (n = 86) articles discussing telehealth applications with respect to (i) control (n = 25), (ii) technology (n = 14) and (iii) medical procedure (n = 47). Since the beginning of the pandemic, telehealth has been presented in diverse cases. However, it still warrants further attention. Regardless of category, the articles focused on the challenges which hinder the maximisation of telehealth in such times and how to address them. With the rapid increase in the utilization of telehealth in different specialised hospitals and clinics, a potential framework which reflects the authors' implications of the future application and opportunities of telehealth has been established. This article improves our understanding and reveals the full potential of telehealth during these difficult times and beyond.

Detection-based prioritisation: Framework of multi-laboratory characteristics for asymptomatic COVID-19 carriers based on integrated Entropy-TOPSIS methods.

CONTEXT AND BACKGROUND: Corona virus (COVID) has rapidly gained a foothold and caused a global pandemic. Particularists try their best to tackle this global crisis. New challenges outlined from various medical perspectives may require a novel design solution. Asymptomatic COVID-19 carriers show different health conditions and no symptoms; hence, a differentiation process is required to avert the risk of chronic virus carriers. OBJECTIVES: Laboratory criteria and patient dataset are compulsory in constructing a new framework. Prioritisation is a popular topic and a complex issue for patients with COVID-19, especially for asymptomatic carriers due to multi-laboratory criteria, criterion importance and trade-off amongst these criteria. This study presents new integrated decision-making framework that handles the prioritisation of patients with COVID-19 and can detect the health conditions of asymptomatic carriers. METHODS: The methodology includes four phases. Firstly, eight important laboratory criteria are chosen using two feature selection approaches. Real and simulation datasets from various medical perspectives are integrated to produce a new dataset involving 56 patients with different health conditions and can be used to check asymptomatic cases that can be detected within the prioritisation configuration. The first phase aims to develop a new decision matrix depending on the intersection between 'multi-laboratory criteria' and 'COVID-19 patient list'. In the second phase, entropy is utilised to set the objective weight, and TOPSIS is adapted to prioritise patients in the third phase. Finally, objective validation is performed. RESULTS: The patients are prioritised based on the selected criteria in descending order of health situation starting from the worst to the best. The proposed framework can discriminate among mild, serious and critical conditions and put patients in a queue while considering asymptomatic carriers. Validation findings revealed that the patients are classified into four equal groups and showed significant differences in their scores, indicating the validity of ranking. CONCLUSIONS: This study implies and discusses the numerous benefits of the suggested framework in detecting/recognising the health condition of patients prior to discharge, supporting the hospitalisation characteristics, managing patient care and optimising clinical prediction rule.

Role of biological Data Mining and Machine Learning Techniques in Detecting and Diagnosing the Novel Coronavirus (COVID-19): A Systematic Review.

Coronaviruses (CoVs) are a large family of viruses that are common in many animal species, including camels, cattle, cats and bats. Animal CoVs, such as Middle East respiratory syndrome-CoV, severe acute respiratory syndrome (SARS)-CoV, and the new virus named SARS-CoV-2, rarely infect and spread among humans. On January 30, 2020, the International Health Regulations Emergency Committee of the World Health Organisation declared the outbreak of the resulting disease from this new CoV called 'COVID-19', as a 'public health emergency of international concern'. This global pandemic has affected almost the whole planet and caused the death of more than 315,131 patients as of the date of this article. In this context, publishers, journals and researchers are urged to research different domains and stop the spread of this deadly virus. The increasing interest in developing artificial intelligence (AI) applications has addressed several medical problems. However, such applications remain insufficient given the high potential threat posed by this virus to global public health. This systematic review addresses automated AI applications based on data mining and machine learning (ML) algorithms for detecting and diagnosing COVID-19. We aimed to obtain an overview of this critical virus, address the limitations of utilising data mining and ML algorithms, and provide the health sector with the benefits of this technique. We used five databases, namely, IEEE Xplore, Web of Science, PubMed, ScienceDirect and Scopus and performed three sequences of search queries between 2010 and 2020. Accurate exclusion criteria and selection strategy were applied to screen the obtained 1305 articles. Only eight articles were fully evaluated and included in this review, and this number only emphasised the insufficiency of research in this important area. After analysing all included studies, the results were distributed following the year of publication and the commonly used data mining and ML algorithms. The results found in all papers were discussed to find the gaps in all reviewed papers. Characteristics, such as motivations, challenges, limitations, recommendations, case studies, and features and classes used, were analysed in detail. This study reviewed the state-of-the-art techniques for CoV prediction algorithms based on data mining and ML assessment. The reliability and acceptability of extracted information and datasets from implemented technologies in the literature were considered. Findings showed that researchers must proceed with insights they gain, focus on identifying solutions for CoV problems, and introduce new improvements. The growing emphasis on data mining and ML techniques in medical fields can provide the right environment for change and improvement.