Diversity in pulmonary rehabilitation clinical trials: a systematic review of the literature.

BACKGROUND: Underrepresentation of minority groups in clinical trials may hinder the potential benefits of pulmonary rehabilitation (PR) programs for individuals with chronic obstructive pulmonary disease (COPD). The aim of this work was to determine whether participants in PR randomized control trials (RCTs) conducted in the U.S.A., Canada, the UK, and Australia are representative of ethnicity, sex, gender, and sociodemographic characteristics. RESEARCH DESIGN: A systematic search was performed for relevant literature from inception to December 2022. Titles and abstracts were screened before undergoing a full article review. Relevant data on reporting of age, sex, gender, ethnicity, and sociodemographic characteristics of participants was extracted. RESULTS: Thirty-six RCTs met the inclusion criteria. Only 6% of publications reported on ethnicity, with ≥90% of participants reported as 'White.' All 36 papers reported on age, with the mean between 60 and 69 years old. Thirty-five studies reported on sex (97%), with the majority (67%) reporting more male than female participants. There was no mention of different genders in any paper. Other sociodemographic factors were reported in 7 (19%) papers. CONCLUSIONS: Inclusivity and representation in clinical trials are essential to ensure that research findings are generalizable. Clinical trialists need to consider the demographics of today's society during recruitment.

Gender comparisons of young adults' eating behavior regulation: Re-examination of the Regulation of Eating Behavior Scale (REBS).

The aim of this study was to evaluate the psychometric properties of the Regulation of Eating Behavior Scale (REBS) in mixed-gender, American samples and to evaluate how responses differed across male and female respondents. Responses were examined in a sample of 535 undergraduate students in the Southeastern United States. A confirmatory factor analysis was used to confirm the predicted factor structure; male and female participants were analyzed in a multi-group, unconstrained configural model, with male and female participants analyzed simultaneously to allow for multi-group comparisons within the same model. Additional analyses evaluated measurement invariance, reliability of the measure in the new sample, gender differences in subscale scores, and correlations across factors. Results of confirmatory factor analysis, multi-group by gender comparisons suggested that the factor structure did not vary across genders. In addition, factor structure was consistent with the findings of the original studies examining the psychometric property of the REBS, with the exception of the 'introjected regulation' subscale, which measures regulation of eating behaviors to avoid self-enforced consequences. Consistent with expectations, female participants' ratings were higher, on average, on more autonomous forms of eating regulation; however, contrary to expectations, scores did not differ significantly between males and females on more external forms of eating regulation. Conclusions, limitations, and implications are discussed.