1.
Science
; 152(3725): 1080-2, 1966 May 20.
Artigo
em Inglês
| MEDLINE
| ID: mdl-5931455
RESUMO
In a cell-free system of pigeon erythrocyte nuclei high concentrations of oxygen inhibit globin synthesis because of the inhibition of heme synthesis, which is required for globin synthesis. The effect of heme in overcoming the inhibition of globin synthesis by oxygen is manifested only during the first few minutes of incubation. This period represents the time during which the system is being warmed from 4 degrees to 37 degrees C. The effect of heme seems to be upon some initial assembly or structural process.