Determination of safflor yellow A by RP-HPLC and resources quality comparison in Carthamus tinctorius / 中国中药杂志

<p><b>OBJECTIVE</b>To provide the basis for establishing evaluation criterion, selecting good strains and carring out good agricultural practice of the crude drug.</p><p><b>METHOD</b>Representative 22 varieties of Carthamus tinctorius were selected and cultivated in different ecological localities and different years. And the content of safflor yellow A in their corollas were measured by RP-HPLC to compare the differences and their genetic stabilities among varieties.</p><p><b>RESULT</b>The range of of safflor yellow A content was 0.70%-1.85% which were varied among varieties (P < 0.01). The content of safflor yellow A in varieties Yutai Honghua, Hefei Honghua, Rucheng Honghua were higher than in others.</p><p><b>CONCLUSION</b>The effective compound safflor yellow A in C. tinctorius was one of the main quality evaluation criterions. Varieties Yutai Honghua, Hefei Honghua and Rucheng Honghua were good resources.</p>

Experimental studies of Panax notoginseng saponins and Ginkgo biloba extracts on preventing acute oxygen toxicity / 中国应用生理学杂志

<p><b>AIM</b>To investigate the preventive effects of Panax notoginseng saponins (PNS) and Ginkgo biloba extracts (GbE) on acute oxygen toxicity and the possible mechanisms.</p><p><b>METHODS</b>Mice were injected intraperitoneally with PNS and GbE for 5 days, then were exposed to 500 kPa hyperbaric oxygen (HBO) for 60 min, the convulsion latency, times and interval were observed. Moreover, reactive oxygen (RO) unit, MDA, NO, GSH levels and GSH-Px, CAT, MAO activities of mice brain were determined after they were exposed to HBO for 15 min.</p><p><b>RESULTS</b>PNS and GbE could markedly prolong the convulsion latency and interval, reduce convulsion times, decrease contents of MDA and NO in mice brain, keep RO unit, GSH and GSH-Px at higher levels, but had no effects on CAT and MAO activities.</p><p><b>CONCLUSION</b>PNS and GbE could effectively prevent acute oxygen toxicity, which were related to their antioxidant activities.</p>

A new alkaloids isolated from tetraploidy banlangen / 药学学报

<p><b>AIM</b>To investigate the chemical constituents of tetraploidy Banlangen (Isatis indigotica Fort.).</p><p><b>METHODS</b>Compounds were separated by chromatography on silica gel. Their structures were determined by spectral analysis and chemical evidence.</p><p><b>RESULTS</b>Three compounds were isolated. Their structures were identified as (E)-2-[(3'-indole) cyanomethylene]-3-indolinone (I), 2-(4-hydroxy-3-methoxyphenyl)-4-[(4-hydroxy-3-methoxy-phenyl)-methyl]-3- hydroxymethyl-tetrahydro-furan (II) and 2-methoxy-4-[tetrahydro-4-[(4-hydroxy-3-methoxy-phenyl)-methyl]-3- hydroxymethyl-2-furanyl] phenyl-1-O-beta-D-glucopyranoside (III).</p><p><b>CONCLUSION</b>Compound I is a new compound.</p>