[The surgical treatments and clinical characteristics of snoring with epiglottis collapse].

Objective:The aim of this study is to summary the characteristics of sleep breath disorder patients with epiglottis collapse and find out the way to treat them with surgery.Method:This is a retrospective study. There were eighteen patients who complained of snoring and somnolence, as well as had undergone DISE. Eight of them were diagnosed as epiglottis collapse. We analysis the clinical features, surgical treatments and prognosis of these eight patents, and compare their BMI, shape of epiglottis and AHI with the patients without epiglottis collapse. Result: Patients with epiglottis collapse usually complained of breathless during sleeping. The shape of their epiglottis was mainly flat and wide, as the cure of the upper margin of their epiglottises shows significant difference with those who are without epiglottis collapse(P=0.03,0.04).DISE is the diagnosis examination. The primary surgical treatment is Epiglottoplasty. Conclusion: It's not uncommon to see epiglottis collapse clinically. Whenever we meet the particular clinical manifestation,the diagnose of epiglottis collapse should be taken into consideration. DISE is the diagnosis examination. Epiglottoplasty can treat them to some degree.

[The current situation and influencing factors of self efficacy in patients with differentiated thyroid cancer treated with radioactive iodine].

Objective:To evaluate the level of self management efficacy of differentiated thyroid cancer patients with RAI, and to analyze the influencing factors.Method:The Chinese version of SUPHH questionnaire, medical coping questionnaire, hospital anxiety and depression scale and patients general condition questionnaire were used to investigate 363 patients.Result:The self-management efficacy score of the patients is 89.71±19.45. The results of multiple linear regression showed that the depression, face, avoidance, yield, character, pathological stage and the knowledge were the main influencing factors of self management efficacy.Conclusion:The sense of self management efficacy of differentiated thyroid cancer patients with the RAI treatment is in the middle level, and needs to be improved. Clinical health care workers can refer to the factors and help patients to develop disease self-management programs and finally to improve the quality of patients life.

Association of genetic polymorphisms of SAA1 (rs12218) with myocardial infarction in a Chinese population.

Previous studies suggested that genetic polymorphisms of serum amyloid A (SAA) were associated with carotid atherosclerosis. However, the relationship between genetic polymorphisms of SAA and myocardial infarction (MI) remains unclear. In the present study, we analyzed a polymorphism (rs12218) in the SAA1 gene in 840 MI patients and 840 healthy subjects by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method. We found that the rs12218 CC+CT genotype was more frequent among MI patients than among healthy controls (61.1% vs 41.9%; P < 0.001). Multivariate regression analysis showed that after adjustment for gender, age, smoking, drinking, hypertension, and diabetes, the difference remained significant (P < 0.001, odds ratio = 3.332, 95% confidence interval = 1.781-9.231). Therefore, we concluded that genetic polymorphisms of SAA1 may be a genetic marker of MI in the Chinese population.