RESUMO
From the leaves of Cleome chelidonii L.f., two new flavonol glycosides, named cleomesides A (1) and B (2), and four known compounds, quercetin 3-O-ß-glucopyranosyl(1 â 2)-α-rhamnoside-7-O-α-rhamnoside (3), ethyl α-galactopyranoside (4), adenine (5) and glycerol monostearate (6), were isolated. The structures of all isolated compounds (1-6) were determined by NMR spectroscopy and mass spectrometry. The data of known compounds (3-6) were further compared with the reported data for these compounds.
Assuntos
Cleome/química , Flavonóis/isolamento & purificação , Glicosídeos/isolamento & purificação , Flavonóis/química , Glicosídeos/química , Estrutura Molecular , Ressonância Magnética Nuclear Biomolecular , Folhas de Planta/química , Quercetina/análogos & derivados , Quercetina/química , Quercetina/isolamento & purificaçãoRESUMO
Two new phenyl glycosides, mangliesides A and B (1, 2), a new ionol glycoside, manglieside C (3), two new lignan glycosides, mangliesides D and E (4, 5), were isolated from the leaves of Manglietia phuthoensis, along with two known lignans, 3-methoxymagnolol (6) and obovatol (7). Their structures were established by means of 1D and 2D NMR, electrospray ionization (ESI)-MS and HR-ESI-MS experiments. Among them, compounds 2 and 5 significantly (p<0.05) increased the growth and differentiation of osteoblastic MC3T3-E1 cells in vitro.