RESUMO
This Letter reports the electro-optical (EO) effect of Poly(3-hexylthiophene-2,5-diyl) (P3HT) nanofibers colloid in a polymer micro-fluidic EO cell. P3HT nanofibers are high aspect ratio semiconducting nanostructures, and can be collectively aligned by an external alternating electric field. Optical transmission modulated by the electric field is a manifestation of the electro-optical effect due to high inner crystallinity of P3HT nanofibers. According to our results, the degree of alignment reaches a maximum at 0.6 V/µm of electric field strength, implying a big polarizability value due to geometry and electrical properties of P3HT nanofibers. We believe that one-dimensional crystalline organic nanostructures have a large potential in EO devices due to their significant anisotropy, wide variety of properties, low actuation voltages, and opportunity to be tailored via adjustment of the fabrication process.
RESUMO
Point-of-care diagnostic devices typically require six distinct qualities: they must deliver at least the same sensitivity and selectivity, and for a cost per assay no greater than that of today's central lab technologies, deliver results in a short period of time (ã15 min at GP; ã2h in hospital), be portable or at least small in scale, and require no or extremely little sample preparation. State-of-the-art devices deliver information of several markers in the same measurement.
Assuntos
Dispositivos Lab-On-A-Chip , Técnicas Analíticas Microfluídicas , Sistemas Automatizados de Assistência Junto ao Leito , Biomarcadores/análise , DNA Bacteriano/isolamento & purificação , Humanos , Técnicas Microbiológicas/métodos , Técnicas Analíticas Microfluídicas/instrumentação , Técnicas Analíticas Microfluídicas/métodos , Sensibilidade e Especificidade , Detecção do Abuso de Substâncias , Transdutores , Vírus/isolamento & purificaçãoRESUMO
In an attempt to evaluate the effect of conservative treatment in 33 patients with longstanding symptoms from the joint and later subjected to temporomandibular joint surgery, a retrospective study was made based on careful case records and personal follow-up. The treatment period varied widely between the patients but was on average 2.5 years. The result of the conservative treatment in these patients was, however, very slight and limited to a minor increase in mouth-opening capacity. All TMJ-patients, including those with the diagnosis ADD and suspected ankylosis, ought to have a strict treatment and follow-up programme in order to reduce doctor's delay if and when surgical intervention should be necessary. Efforts should be focused on development of diagnostic methods to support the selection of patients for TMJ surgery earlier so as to avoid prolonged unsuccessful conservative treatment.
