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1.
Obstet Med ; 17(1): 47-49, 2024 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-38660328

RESUMO

Ustekinumab (USK) was used in the treatment of two pregnant patients with Crohn's disease. It was given in the third trimester and restarted postnatally for both women. One woman remained on USK and in remission throughout pregnancy. The second woman, took a treatment break, flared, and then had remission induced with reintroduction of USK. Both women delivered healthy term infants. The interval from last dose to birth was 11 and 8 weeks respectively. Interestingly, USK levels in cord blood was observed in higher concentrations than in the maternal serum taken in third trimester. While no adverse effect in infants has been observed, clinicians should remain aware of fetal transfer when using USK in pregnancy. An evaluation of risk and benefit may favour continuing USK in pregnancy in patients with refractory disease.

3.
Eur J Gastroenterol Hepatol ; 32(2): 157-162, 2021 02 01.
Artigo em Inglês | MEDLINE | ID: mdl-32804857

RESUMO

OBJECTIVE: Healthcare resources are finite. Value in healthcare can be defined as patient health outcomes achieved per monetary unit spent. Attempts have been made to quantify the value of luminal endoscopy, but there is little in the medical literature describing the value of the complex therapeutic endoscopic activity. This study aimed to characterise the value of endoscopic ultrasound (EUS)-guided drainage of pancreatic fluid collections (PFCs) with either plastic or lumen-apposing metal stents (LAMSs). METHODS: This is a single-centre, retrospective-prospective comparative study of 39 patients, who underwent EUS-guided PFC drainage between 2009 and 2018. Procedure value was calculated using the formula Q/(T/C), where Q is the quality of procedure adjusted for complications, T procedure duration and C is the complexity adjustment. Quality and complexity were estimated on a 1-4 Likert scale based on the American Society for Gastrointestinal Endoscopy criteria. Time (in minutes) was recorded from the patient entering and leaving the procedure room. Endoscopy time calculated from procedure time was considered a surrogate marker of cost as individual components of procedure cost were not itemized. RESULTS: Of 39 identified patients who underwent EUS-guided PFC drainage, 11 received double pigtail plastic stents (DPPSs) and 28 received LAMSs. The two groups were comparable in age, gender and aetiology. Nearly 40% of the LAMS interventions were considered high value but only 11% of the plastic stent interventions achieved the same. The difference predominantly was due to a higher rate of complications and longer procedure time. CONCLUSION: In this single-centre study, EUS-guided PFC drainage using LAMS was found to be a higher value procedure compared to the use of DPPS.


Assuntos
Drenagem , Plásticos , Endoscopia Gastrointestinal , Endossonografia , Humanos , Estudos Prospectivos , Estudos Retrospectivos , Stents , Ultrassonografia de Intervenção
5.
Ir J Med Sci ; 188(2): 497-503, 2019 May.
Artigo em Inglês | MEDLINE | ID: mdl-29998423

RESUMO

BACKGROUND: With the emergence of alternative payment systems replacing the traditional funding models, the value of physician activity is scrutinized more closely. Attempts have been made to quantify the value of endoscopists' activity; there is little in the medical literature describing gastroenterologists' value in the outpatient setting. AIMS: To characterize the value of clinical activity of gastroenterologists in the outpatient setting. METHODS: The value of clinical activity of ten gastroenterologists in an academic medical center was estimated. Value was defined as Q (quality of clinical care) divided by TA (duration of outpatient visit adjusted for complexity level); TA served as a surrogate measure of the cost of the clinician's services. Medical records of each patient's clinical visit were reviewed and graded independently by three staff gastroenterologists; each reviewer was blinded to the identity of the physician and to other reviewers' scores. RESULTS: Over consecutive weeks, the clinical records of 307 patients who were seen by ten gastroenterologists were reviewed and graded for quality (Q) and complexity (C); the duration of each visit (T) was recorded. Each physician saw a mean of 31 patients; mean physician value varied from 0.28 to 0.87. More senior physicians demonstrated higher levels of value. CONCLUSION: Measurement of the value of clinical activity represents an important component of gastroenterologists' performance. There was a threefold variation among physician levels of value with more experienced clinicians demonstrating higher value levels. Further studies will be required to more clearly define valid metrics for physician value.


Assuntos
Gastroenterologistas/normas , Qualidade da Assistência à Saúde/normas , Feminino , Humanos , Masculino , Pacientes Ambulatoriais
6.
Eur J Gastroenterol Hepatol ; 30(7): 718-721, 2018 07.
Artigo em Inglês | MEDLINE | ID: mdl-29642093

RESUMO

INTRODUCTION: As finite healthcare resources come under pressure, the value of physician activity is assuming increasing importance. The value in healthcare can be defined as patient health outcomes achieved per monetary unit spent. Even though some attempts have been made to quantify the value of clinician activity, there is little in the medical literature describing the importance of endoscopists' activity. This study aimed to characterize the value of endoscopic retrograde cholangiopancreatography (ERCP) performance of five gastroenterologists. PATIENTS AND METHODS: We carried out a retrospective-prospective cohort study using the databases of patients undergoing ERCP between September 2014 and March 2017. We collected data from 1070 patients who underwent ERCP comparing value among the ERCPists at index ERCP. Procedure value was calculated using the formula Q/(T/C), where Q is the quality of procedure, T is the duration of procedure and C is the adjusted for complexity level. Quality and complexity were derived on a 1-4 Likert scale on the basis of American Society for Gastrointestinal Endoscopy criteria; time was recorded (in min) from intubation to extubation. Endoscopist time calculated from procedure time was considered a surrogate marker of cost as individual components of procedure cost were not itemized. RESULTS: In total, 590 procedures were analysed: 465 retrospectively over 24 months and 125 prospectively over 6 months. There was a 32% variation in the value of endoscopist activity in a more substantial retrospective cohort, with an even more considerable 73% variation in a smaller prospective arm. CONCLUSION: In an analysis of greater than 1000 ERCPs by a small cohort of experienced ERCPists, there was a wide variation in the value of endoscopist activity. Although the precision of estimating procedural costs needs further refinement, these findings show the ability to stratify ERCPists on the basis of the value their activity. As healthcare costs are scrutinized more closely, such value measurements are likely to become more relevant.


Assuntos
Colangiopancreatografia Retrógrada Endoscópica/economia , Gastroenterologistas/economia , Custos de Cuidados de Saúde , Indicadores de Qualidade em Assistência à Saúde/economia , Seguro de Saúde Baseado em Valor/economia , Colangiopancreatografia Retrógrada Endoscópica/efeitos adversos , Competência Clínica/economia , Análise Custo-Benefício , Bases de Dados Factuais , Humanos , Modelos Econômicos , Estudos Prospectivos , Estudos Retrospectivos , Centros de Atenção Terciária/economia , Fatores de Tempo
7.
Am J Gastroenterol ; 111(9): 1274-5, 2016 09.
Artigo em Inglês | MEDLINE | ID: mdl-27580777

RESUMO

With the growing pressure on physicians to maximize efficiency and enhance the value of clinical practice, overbooking endoscopy schedules appears to hold promise, if implemented strategically, to enhance patient access for endoscopy procedures. Overbooking is a practice that has been routinely utilized by the airline industry to offset losses incurred by passengers not showing for flights, and there is evidence emerging in the medical literature that a similar approach can be utilized in health care. In the context of endoscopy practice, a key aspect of implementing overbooking successfully is the ability to precisely and accurately predict which patients will have a high likelihood of not attending for their procedure, thereby allowing their slots to be double booked while minimizing the likelihood of overburdening the practice with excessive workload. Despite the potential efficiencies that can be realized with overbooking in health care, it remains important not to neglect the needs of those patients who predictably and consistently fail to attend for health-care appointments.


Assuntos
Agendamento de Consultas , Endoscopia , Eficiência , Humanos
8.
Dig Dis Sci ; 60(8): 2280-6, 2015 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-25840918

RESUMO

UNLABELLED: Proton pump inhibitors (PPIs) are used to treat upper gastrointestinal tract disorders. Their efficacy and perceived safety have led to widespread prescription. This is not without effect, in terms of adverse events and resource utilization. AIM: To prospectively assess oral PPI prescription in hospitalized patients. METHODS: PPI prescription in consecutive hospitalized patients was assessed. Indication and dose were assessed by patient interview and medical record review. Comparisons with current published prescribing guidelines were made. RESULTS: Four hundred and forty-seven patients were included. 57.5 % were prescribed PPIs. 26.8 % prescriptions were for inappropriate or unclear indications. 68.4 % were on higher doses than guidelines recommended, of which 41.6 % could have undergone dose reduction, and 26.5 % discontinued. In a multivariate analysis, age, gender, and length of stay had no association with PPI prescription. Although aspirin use was appropriately associated with PPI prescription (RR: 1.8, 95 % CI 1.127-3.69; p < 0.05), the PPI was often given at higher than recommended doses (p < 0.001). This may reflect older age and multiple risk factors in this subset. Surgical patients commenced more PPIs and at higher dosages (p < 0.001). Omeprazole and lansoprazole were most often inappropriately prescribed (p < 0.01, p < 0.001, respectively). CONCLUSION: Inappropriate PPI therapy is still a problem in hospitals, though it appears to be at a lower level compared with previous studies. Awareness of evidence-based guidelines and targeted medicine reconciliation strategies are essential for cost-effective and safe use of these medications.


Assuntos
Prescrição Inadequada/estatística & dados numéricos , Inibidores da Bomba de Prótons/uso terapêutico , Administração Oral , Idoso , Estudos Transversais , Dispepsia/tratamento farmacológico , Dispepsia/etiologia , Feminino , Refluxo Gastroesofágico/tratamento farmacológico , Humanos , Masculino , Pessoa de Meia-Idade , Guias de Prática Clínica como Assunto , Estudos Prospectivos , Inibidores da Bomba de Prótons/administração & dosagem
12.
Clin Gastroenterol Hepatol ; 13(3): 609-12, 2015 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-25151259

RESUMO

The Centers for Medicare and Medicaid Services recently published data on Medicare payments to physicians for 2012. We investigated regional variations in payments to gastroenterologists and evaluated whether payments correlated with the number of Medicare patients in each state. We found that the mean payment per gastroenterologist in each state ranged from $35,293 in Minnesota to $175,028 in Mississippi. Adjusted per-physician payments ranged from $11 per patient in Hawaii to $62 per patient in Washington, DC. There was no correlation between the mean per-physician payment and the mean number of Medicare patients per physician (r = 0.09), there also was no correlation between the mean per-physician payment and the overall mean per-capita health care costs for each state (r = -0.22). There was a 5.6-fold difference between the states with the lowest and highest adjusted Medicare payments to gastroenterologists. Therefore, the Centers for Medicare and Medicaid Services payments do not appear to be associated with the volume of Medicare beneficiaries or overall per-capita health care costs for each state.


Assuntos
Centers for Medicare and Medicaid Services, U.S. , Gastroenteropatias/economia , Gastroenteropatias/terapia , Custos de Cuidados de Saúde , Serviços de Saúde/economia , Benefícios do Seguro/estatística & dados numéricos , Serviços de Saúde/estatística & dados numéricos , Humanos , Estados Unidos
13.
Clin Gastroenterol Hepatol ; 12(11): 1953-5, 2014 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-24907501

RESUMO

There is growing awareness of the price disparities for equivalent services in healthcare. We aimed to characterize regional variations in fees charged by gastroenterologists in Manhattan, NY. All private practice gastroenterologists in Manhattan were contacted and asked what they charge fee-paying patients for initial consultations for nonspecific gastrointestinal symptoms. Cost information was obtained from 89 offices, and practices were classified on the basis of location in Manhattan. We observed significant regional variation; gastroenterologists on the Upper East Side (1.20-fold the overall mean) charged more than twice as those on the Upper West Side (0.58-fold the mean) and 50% more than gastroenterologists in South Manhattan (0.76-fold the mean). The coefficient of variation was 46%; the most expensive gastroenterologist charged 14-fold more than the least expensive. We provide evidence for significant regional variation in prices for medical services. Future studies are needed to characterize regional price variations in other aspects of healthcare.


Assuntos
Atitude do Pessoal de Saúde , Honorários e Preços/estatística & dados numéricos , Gastroenterologia , Serviços de Saúde/economia , Especialização , Custos e Análise de Custo , Humanos , Cidade de Nova Iorque
17.
Dig Endosc ; 25(4): 392-6, 2013 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-23808945

RESUMO

BACKGROUND AND AIM: Gastric antral vascular ectasia (GAVE) or 'watermelon stomach' is a rare and often misdiagnosed cause of occult upper gastrointestinal bleeding. Treatment includes conservative measures such as transfusion and endoscopic therapy. A recent report suggests that endoscopic band ligation (EBL) offers an effective alternative treatment. The aim of the present study is to demonstrate our experiences with this novel technique, and to compare argon plasma coagulation (APC) with EBL in terms of safety and efficacy. METHODS: A retrospective analysis of all endoscopies with a diagnosis of GAVE was carried out between 2004 and 2010. Case records were examined for information pertaining to the number of procedures carried out, mean blood transfusions, mean hemoglobin, and complications. RESULTS: A total of 23 cases of GAVE were treated. The mean age was 73.9 (55-89) years. Female to male ratio was 17:6 and mean follow up was 26 months. Eight patients were treated with EBL with a mean number of treatments of 2.5 (1-5). This resulted in a statistically significant improvement in the endoscopic appearance and a trend towards fewer transfusions. Of the eight patients treated with EBL, six (75%) patients had previously failed APC treatment despite having a mean of 4.7 sessions. Band ligation was not associated with any short- or medium-term complications. The 15 patients who had APC alone had a mean of four (1-11) treatments. Only seven (46.7%) of these patients had any endoscopic improvement with a mean of four sessions. CONCLUSIONS: EBL represents a safe and effective treatment for GAVE.


Assuntos
Ectasia Vascular Gástrica Antral/cirurgia , Hemorragia Gastrointestinal/prevenção & controle , Gastroscopia/métodos , Idoso , Idoso de 80 Anos ou mais , Feminino , Seguimentos , Ectasia Vascular Gástrica Antral/complicações , Ectasia Vascular Gástrica Antral/diagnóstico , Hemorragia Gastrointestinal/etiologia , Humanos , Ligadura/métodos , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Resultado do Tratamento
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