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Andrologia ; 51(2): e13180, 2019 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-30350415

RESUMO

Cassia auriculata is a commonly found plant in Asia, widely used in Ayurveda and Siddha medicines as a tonic, astringent and in general for diabetes. Herbal tea made from this plant has been marketed as a product for restoring sexual vitality, to increase sperm count and counteract ejaculatory disorders. However, the scientific evidences are scarce to prove this concept. Here, we examined the effect of hydro-alcoholic extract obtained from C. auriculata flower upon the expression of male Wistar albino rat's sexual behaviour. Sildenafil was used as a positive control. Penile erection index (PEI), mount latency (ML), intromission latency (IL), ejaculation latency (EL), mounting frequency (MF), intromission frequency (IF), ejaculation frequency (EF) and post-ejaculatory interval (PEjI) were recorded for days 0, 7, 14 and 28 and also after the withdrawal of the treatment on days 7 and 15. Significant reduction in ML, IL and PEjI, and increment in EL, PEI, MF, IF and EF were observed (p < 0.05, <0.01). However, neither extract nor sildenafil sustains the effect after withdrawal of the treatment. The present finding demonstrates the aphrodisiac potential of hydro-alcoholic extract of C. auriculata flower in vivo and lends support to the traditional utilisation as a sexual stimulating agent.


Assuntos
Afrodisíacos/farmacologia , Cassia , Ejaculação/efeitos dos fármacos , Ereção Peniana/efeitos dos fármacos , Extratos Vegetais/farmacologia , Comportamento Sexual Animal/efeitos dos fármacos , Animais , Masculino , Ratos , Ratos Wistar
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