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1.
PLoS One ; 14(12): e0226000, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31810079

RESUMO

Learned Categorical Perception (CP) occurs when the members of different categories come to look more dissimilar ("between-category separation") and/or members of the same category come to look more similar ("within-category compression") after a new category has been learned. To measure learned CP and its physiological correlates we compared dissimilarity judgments and Event Related Potentials (ERPs) before and after learning to sort multi-featured visual textures into two categories by trial and error with corrective feedback. With the same number of training trials and feedback, about half the subjects succeeded in learning the categories ("Learners": criterion 80% accuracy) and the rest did not ("Non-Learners"). At both lower and higher levels of difficulty, successful Learners showed significant between-category separation-and, to a lesser extent, within-category compression-in pairwise dissimilarity judgments after learning, compared to before; their late parietal ERP positivity (LPC, usually interpreted as decisional) also increased and their occipital N1 amplitude (usually interpreted as perceptual) decreased. LPC amplitude increased with response accuracy and N1 amplitude decreased with between-category separation for the Learners. Non-Learners showed no significant changes in dissimilarity judgments, LPC or N1, within or between categories. This is behavioral and physiological evidence that category learning can alter perception. We sketch a neural net model predictive of this effect.


Assuntos
Aprendizagem/fisiologia , Percepção Visual , Adolescente , Adulto , Encéfalo/fisiologia , Mapeamento Encefálico , Eletroencefalografia , Potenciais Evocados , Feminino , Humanos , Masculino , Estimulação Luminosa , Adulto Jovem
2.
Behav Brain Sci ; 42: e231, 2019 11 28.
Artigo em Inglês | MEDLINE | ID: mdl-31775946

RESUMO

Brette criticizes the notion of neural coding because it seems to entail that neural signals need to "decoded" by or for some receiver in the head. If that were so, then neural coding would indeed be homuncular (Brette calls it "dualistic"), requiring an entity to decipher the code. But I think Brette's plea to think instead in terms of complex, interactive causal throughput is preaching to the converted. Turing (not Shannon) has already shown the way. In any case, the metaphor of neural coding has little to do with the symbol grounding problem.


Assuntos
Cognição , Metáfora , Encéfalo , Comunicação
3.
Top Cogn Sci ; 8(3): 625-59, 2016 07.
Artigo em Inglês | MEDLINE | ID: mdl-27424842

RESUMO

How many words-and which ones-are sufficient to define all other words? When dictionaries are analyzed as directed graphs with links from defining words to defined words, they reveal a latent structure. Recursively removing all words that are reachable by definition but that do not define any further words reduces the dictionary to a Kernel of about 10% of its size. This is still not the smallest number of words that can define all the rest. About 75% of the Kernel turns out to be its Core, a "Strongly Connected Subset" of words with a definitional path to and from any pair of its words and no word's definition depending on a word outside the set. But the Core cannot define all the rest of the dictionary. The 25% of the Kernel surrounding the Core consists of small strongly connected subsets of words: the Satellites. The size of the smallest set of words that can define all the rest-the graph's "minimum feedback vertex set" or MinSet-is about 1% of the dictionary, about 15% of the Kernel, and part-Core/part-Satellite. But every dictionary has a huge number of MinSets. The Core words are learned earlier, more frequent, and less concrete than the Satellites, which are in turn learned earlier, more frequent, but more concrete than the rest of the Dictionary. In principle, only one MinSet's words would need to be grounded through the sensorimotor capacity to recognize and categorize their referents. In a dual-code sensorimotor/symbolic model of the mental lexicon, the symbolic code could do all the rest through recombinatory definition.


Assuntos
Dicionários como Assunto , Humanos , Aprendizagem , Semântica
4.
Oncotarget ; 7(26): 38999-39016, 2016 Jun 28.
Artigo em Inglês | MEDLINE | ID: mdl-27229915

RESUMO

Much of Alzheimer disease (AD) research has been traditionally based on the use of animals, which have been extensively applied in an effort to both improve our understanding of the pathophysiological mechanisms of the disease and to test novel therapeutic approaches. However, decades of such research have not effectively translated into substantial therapeutic success for human patients. Here we critically discuss these issues in order to determine how existing human-based methods can be applied to study AD pathology and develop novel therapeutics. These methods, which include patient-derived cells, computational analysis and models, together with large-scale epidemiological studies represent novel and exciting tools to enhance and forward AD research. In particular, these methods are helping advance AD research by contributing multifactorial and multidimensional perspectives, especially considering the crucial role played by lifestyle risk factors in the determination of AD risk. In addition to research techniques, we also consider related pitfalls and flaws in the current research funding system. Conversely, we identify encouraging new trends in research and government policy. In light of these new research directions, we provide recommendations regarding prioritization of research funding. The goal of this document is to stimulate scientific and public discussion on the need to explore new avenues in AD research, considering outcome and ethics as core principles to reliably judge traditional research efforts and eventually undertake new research strategies.


Assuntos
Doença de Alzheimer/genética , Doença de Alzheimer/terapia , Pesquisa Biomédica/tendências , Doença de Alzheimer/metabolismo , Animais , Simulação por Computador , Modelos Animais de Doenças , Humanos , Células-Tronco Pluripotentes Induzidas/citologia , National Institutes of Health (U.S.) , Neuroimagem , Projetos de Pesquisa , Apoio à Pesquisa como Assunto , Fatores de Risco , Estados Unidos
7.
PLoS One ; 5(10): e13636, 2010 Oct 18.
Artigo em Inglês | MEDLINE | ID: mdl-20976155

RESUMO

BACKGROUND: Articles whose authors have supplemented subscription-based access to the publisher's version by self-archiving their own final draft to make it accessible free for all on the web ("Open Access", OA) are cited significantly more than articles in the same journal and year that have not been made OA. Some have suggested that this "OA Advantage" may not be causal but just a self-selection bias, because authors preferentially make higher-quality articles OA. To test this we compared self-selective self-archiving with mandatory self-archiving for a sample of 27,197 articles published 2002-2006 in 1,984 journals. METHDOLOGY/PRINCIPAL FINDINGS: The OA Advantage proved just as high for both. Logistic regression analysis showed that the advantage is independent of other correlates of citations (article age; journal impact factor; number of co-authors, references or pages; field; article type; or country) and highest for the most highly cited articles. The OA Advantage is real, independent and causal, but skewed. Its size is indeed correlated with quality, just as citations themselves are (the top 20% of articles receive about 80% of all citations). CONCLUSIONS/SIGNIFICANCE: The OA advantage is greater for the more citable articles, not because of a quality bias from authors self-selecting what to make OA, but because of a quality advantage, from users self-selecting what to use and cite, freed by OA from the constraints of selective accessibility to subscribers only. It is hoped that these findings will help motivate the adoption of OA self-archiving mandates by universities, research institutions and research funders.


Assuntos
Fator de Impacto de Revistas , Internet
8.
Behav Brain Sci ; 33(2-3): 213-4, 2010 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-20584404

RESUMO

Machery suggests that the concept of "concept" is too heterogeneous to serve as a "natural kind" for scientific explanation, so cognitive science should do without concepts. I second the suggestion and propose substituting, in place of concepts, inborn and acquired sensorimotor category-detectors and category-names combined into propositions that define and describe further categories.


Assuntos
Formação de Conceito , Aprendizagem , Percepção , Ciência Cognitiva , Retroalimentação Psicológica , Humanos
10.
Artif Intell Med ; 44(2): 83-9, 2008 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-18930641

RESUMO

Consciousness is feeling, and the problem of consciousness is the problem of explaining how and why some of the functions underlying some of our performance capacities are felt rather than just "functed." But unless we are prepared to assign to feeling a telekinetic power (which all evidence contradicts), feeling cannot be assigned any causal power at all. We cannot explain how or why we feel. Hence the empirical target of cognitive science can only be to scale up to the robotic Turing test, which is to explain all of our performance capacity, but without explaining consciousness or incorporating it in any way in our functional explanation.


Assuntos
Estado de Consciência , Robótica , Inteligência Artificial
11.
Recurso na Internet em Inglês | LIS - Localizador de Informação em Saúde | ID: lis-20885

RESUMO

It brings texts from different authors about open access, its advantages, how to promote it, its impact and other revelant issues related to it. It also have external links.


Assuntos
50111 , Comunicação e Divulgação Científica
12.
Philos Ethics Humanit Med ; 2: 31, 2007 Dec 07.
Artigo em Inglês | MEDLINE | ID: mdl-18067660

RESUMO

The ethical case for Open Access (OA) (free online access) to research findings is especially salient when it is public health that is being compromised by needless access restrictions. But the ethical imperative for OA is far more general: It applies to all scientific and scholarly research findings published in peer-reviewed journals. And peer-to-peer access is far more important than direct public access. Most research is funded so as to be conducted and published, by researchers, in order to be taken up, used, and built upon in further research and applications, again by researchers (pure and applied, including practitioners), for the benefit of the public that funded it - not in order to generate revenue for the peer-reviewed journal publishing industry (nor even because there is a burning public desire to read much of it). Hence OA needs to be mandated, by researchers' institutions and funders, for all research.


Assuntos
Acesso à Informação/ética , Pesquisa Biomédica , Publicações Periódicas como Assunto/ética , Editoração/ética , Bibliometria , Canadá , Humanos , Sistemas On-Line
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