1.
Exp Mol Med
; 35(6): 534-7, 2003 Dec 31.
Artigo
em Inglês
| MEDLINE
| ID: mdl-14749531
RESUMO
The peculiarities of helix-coil transition of DNA at complex-formation with cis-diamminedichlorplatinum (II) (cis-DDP) have been investigated in acidic environment by UV absorbance technique. It is shown that observed features of behavior T (pH) and T(m) (pH) DNA at pH 2.8-3.0 are possible to explain by formation in DNA of pseudo-ring structures at covalent linking of cis-DDP with DNA.
