1.
Am J Obstet Gynecol
; 214(4): 548-549, 2016 Apr.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26692179
2.
Am J Obstet Gynecol
; 213(3): 268-77, 2015 Sep.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25794631
RESUMO
Preeclampsia is a syndrome occurring only in pregnancy characterized by systemic maternal inflammation and associated with the presence of the placenta. How these 2 aspects of the disease are linked has been the subject of numerous theories and ideas. Recently, there has been increasing interest in DNA shed from the placenta into the maternal circulation as a potential agent initiating the inflammatory response. This review will discuss the current evidence and future directions for placental DNA as the linking factor in preeclampsia in the context of other hypotheses.