Assuntos
Desenvolvimento Infantil , Testes Psicológicos , Serviços de Saúde Escolar , Criança , Tchecoslováquia , Educação , Avaliação Educacional , Feminino , Humanos , Masculino , MétodosRESUMO
In a population of (CB X CC)F1 X WB hybrids, a chicken was found with a presumably recombinant haplotype, BR1, whose antigenic products detectable by hemagglutination contained determinants derived from both parental haplotypes, i.e. B1 (from CB) and B2 (from CC). This recombinant bird and its progeny from different crosses were tested by skin grafting, graft-vs.-host (GVH) and mixed lymphocyte reactions (MLR). The results define two regions of the B system, the B-F and the B-G. The B-F region determined serologically defined antigens, histocompatibility antigens, and controlled the GVH and MLR reactions, while the B-G region was responsible only for synthesis of serologically detectable antigens.
Assuntos
Epitopos , Antígenos de Histocompatibilidade , Recombinação Genética , Animais , Galinhas , Feminino , Genótipo , Reação Enxerto-Hospedeiro , Teste de Cultura Mista de Linfócitos , Masculino , Transplante de Pele , Transplante HomólogoRESUMO
51Cr-labelled erythrocytes were injected into young chicks, F1 hybrids of the inbred chicken lines, from hatching to 2 months of age. The onset of immunity was measured by means of elimination of labelled red blood cells. It was found that with the B-locus difference between donors and recipients the immune response developed from 4 days of age to the end of the first week, whereas with the A-locus difference it developed during the second week of life. The onset of immunity is delayed in inbred chickens compared to outbred chickens, because we have used one alloantigen difference.
