1.
J Nat Prod
; 65(7): 1045-8, 2002 Jul.
Artigo
em Inglês
| MEDLINE
| ID: mdl-12141872
RESUMO
The aerial parts of Inula verbascifolia subsp. methanea yielded three new epoxygermacranolides, compounds 1-3, in addition to the previously known 9beta-hydroxyparthenolide. The structures of 1-3 have been elucidated on the basis of their spectral data (MS, CD, 1D and 2D NMR) and by quantum mechanical calculations. The in vitro cytotoxic activity of compounds 1-3 was evaluated against six human solid tumor cell lines.