RESUMO
BACKGROUND: Infra-inguinal revascularization surgery remains one of the most commonly performed major vascular procedures in contemporary practice. Surgical site infections (SSI) are a common cause of morbidity in this patient cohort and generate high rates of limb loss and mortality when vascular graft involvement occurs. An overall reduction in North American SSI has been attributed to the establishment of national benchmarks. A comparable Australasian benchmark does not exist. The purpose of the present study was to assess the methods used by Australasian vascular units to determine SSI rates and to instigate the development of an acceptable benchmark. METHODS: A structured questionnaire pertaining to SSI after infra-inguinal revascularization surgery was sent to 26 Australasian vascular units. Data requested included the number and type of lower extremity revascularization procedures performed. Units were also asked to report the methods employed for defining and detecting wound infections and to document their SSI rate. The incidence of SSI causation by methicillin-resistant Staphylococcus aureus (MRSA) was also sought. RESULTS: The total number of revascularizations performed annually varied from 28 to 179 between units. The SSI rates ranged from 0 to 38%. The incidence of MRSA involvement varied from <1% to 56%. The SSI surveillance methodology varied considerably between units. CONCLUSIONS: The present study confirms the significant incidence of SSI after infra-inguinal revascularization surgery in contemporary vascular practice. Standardized definitions and surveillance protocols are required to facilitate inter- and intrahospital comparisons. A possible benchmark infection rate may be 10-20%.
Assuntos
Perna (Membro)/irrigação sanguínea , Infecção da Ferida Cirúrgica/epidemiologia , Procedimentos Cirúrgicos Vasculares , Austrália/epidemiologia , Benchmarking , Humanos , Canal Inguinal , Resistência a Meticilina , Infecções Estafilocócicas/epidemiologia , Inquéritos e QuestionáriosRESUMO
BACKGROUND: The release of catabolic stress hormones because of surgical trauma leads to a breakdown of fats, proteins, and carbohydrate stores and interference with immune function. This can delay wound healing and may increase the risk of systemic inflammatory response syndrome (SIRS)/sepsis and postoperative complications. Minimally invasive surgery can attenuate this response. Our purpose was (1) to compare neuroendocrine responses in patients undergoing open abdominal aneurysm repair with those in patients undergoing endovascular aneurysm repair (EVAR), (2) to compare the incidence of SIRS/sepsis and all complications in these two groups, and (3) to look at the relationship between procedure type, neuroendocrine response, and incidence of SIRS/sepsis and complications. METHODS: Forty-six patients who underwent open repair and 19 who underwent EVAR were studied. A baseline (T1) 24-hour urine save was undertaken in the week before admission, and a second 24-hour save (T2) commenced at anesthetic induction to measure cortisol and catecholamines. The incidences of SIRS/sepsis and complications were recorded. RESULTS: Significant ( P = .001) increases in cortisol and adrenaline from T1 to T2 occurred in all patients. Controlling for the type of anesthetic, the administration of exogenous inotropes, and beta-adrenoreceptor antagonists (beta-blockers), there was a significant difference in cortisol (T2) associated with the type of procedure. Responses were greater in open patients in comparison to EVAR patients (F 3,61 = 5.0; P = .03). The incidence of SIRS (50% vs 32%), sepsis (26% vs 5%), and all complications (76% vs 32%) was significantly ( P = .02) higher in open than EVAR patients, respectively. Cortisol and adrenaline measured for 24 hours, commencing at the time of induction, tended to be higher in patients with SIRS/sepsis and all complications, but this did not reach significance. CONCLUSIONS: An attenuated glucocorticoid surge characterizes the reduced stress response experienced by patients undergoing EVAR compared with open abdominal aortic aneurysm repair. A reduction in the occurrence of SIRS is a feature of a more favorable postoperative course after an endovascular approach.