1.
Mult Scler Relat Disord
; 26: 74-76, 2018 Nov.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30237107
RESUMO
Natalizumab is a monoclonal antibody licensed for the treatment of relapsing-remitting multiple sclerosis (RRMS). It is known to increase the potential risk of developing progressive multifocal leukoencephalopathy (PML). There is current debate in the literature regarding its association with malignant melanoma. Herein, we report a case of a 55-year old lady with RRMS for whom natalizumab therapy was being considered by her neurologist. Her medical history included a choroidal melanoma which had undergone successful treatment. Additionally, in this case study we discuss the issues regarding malignant melanoma risk and recurrence with natalizumab treatment.
Assuntos
Neoplasias da Coroide/induzido quimicamente , Fatores Imunológicos/efeitos adversos , Melanoma/induzido quimicamente , Esclerose Múltipla Recidivante-Remitente/tratamento farmacológico , Natalizumab/efeitos adversos , Feminino , Humanos , Pessoa de Meia-Idade
2.
Mult Scler Relat Disord
; 3(6): 735-7, 2014 Nov.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25891554