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1.
Appl Radiat Isot ; 88: 221-4, 2014 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-24491682

RESUMO

The near threshold (7)Li(p,n)(7)Be neutrons generated by incident proton energy having Gaussian distribution with mean energies from 1.85 to 1.95MeV, were studied as a practical neutron source for BNCT wherein an RFQ accelerator and a thick Li-target are used. Gaussian energy distributions with the standard deviation of 0, 10, 20 and 40keV for mean proton energies from 1.85 to 1.95MeV were surveyed in 0.01MeV increments. A thick liquid Li-target whose dimensions were established in our previous experiments (i.e., 1mm-thick with 50mm width and 50mm length) was considered in this study. The suitable incident proton energy and physical dimensions of Pb layer which serves as a gamma absorber and a Polyethylene layer which is used as a BDE were surveyed by means of the concepts of TPD. Dose distribution were calculated by using MCNP5. A proton beam with mean energy of 1.92MeV and a Gaussian energy distribution with a standard deviation of 20keV at a current of 10mA was selected from the viewpoint of irradiation time and practically achievable proton current. The suitable thicknesses of Pb gamma absorber was estimated to be about 3cm. The estimated thickness of the polyethylene BDE was about 24mm for an ideal proton current of 13mA, and was 18mm for a practical proton current of 10mA.


Assuntos
Berílio/química , Terapia por Captura de Nêutron de Boro/instrumentação , Lítio/química , Modelos Estatísticos , Nêutrons/uso terapêutico , Aceleradores de Partículas/instrumentação , Absorção de Radiação , Berílio/efeitos da radiação , Simulação por Computador , Desenho de Equipamento , Análise de Falha de Equipamento , Lítio/efeitos da radiação , Teste de Materiais , Distribuição Normal , Prótons , Radiometria , Dosagem Radioterapêutica , Espalhamento de Radiação
2.
Appl Radiat Isot ; 88: 198-202, 2014 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-24412425

RESUMO

A feasibility study on liquid lithium target in the form of a flowing film was performed to evaluate its potential use as a neutron generation target of (7)Li(p,n)(7)Be reaction in BNCT. The target is a windowless-type flowing film on a concave wall. Its configuration was adapted for a proton beam which is 30mm in diameter and with energy and current of up to 3MeV and 20mA, respectively. The flowing film of liquid lithium was 0.6mm in thickness, 50mm in width and 50mm in length. The shapes of the nozzle and concave back wall, which create a stable flowing film jet, were decided based on water experiments. A lithium hydrodynamic experiment was performed to observe the stability of liquid lithium flow behavior. The flowing film of liquid lithium was found to be feasible at temperatures below the liquid lithium boiling saturation of 342°C at the surface pressure of 1×10(-3)Pa. Using a proto-type liquid lithium-circulating loop for BNCT, the stability of the film flow was confirmed for velocities up to 30m/s at 220°C and 250°C in vacuum at a pressure lower than 10(-3) Pa. It is expected that for practical use, a flowing liquid lithium target of a windowless type can solve the problem of radiation damage and target cooling.


Assuntos
Berílio/química , Terapia por Captura de Nêutron de Boro/instrumentação , Lítio/química , Membranas Artificiais , Aceleradores de Partículas/instrumentação , Radiometria/instrumentação , Berílio/efeitos da radiação , Desenho de Equipamento , Análise de Falha de Equipamento , Lítio/efeitos da radiação , Teste de Materiais , Nêutrons , Dosagem Radioterapêutica , Soluções
3.
Appl Radiat Isot ; 88: 139-42, 2014 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-24433991

RESUMO

The feasibility of a pinhole camera system for online dosimetry in boron neutron capture therapy (BNCT) was studied. A prototype system was designed and built. Prompt γ-rays from the (10)B(n,α)(7)Li reaction from a phantom irradiated with neutrons were detected with the prototype system. An image was reconstructed from the experimental data. The reconstructed image showed a good separation of the two borated regions in the phantom. The counting rates and signal-to-noise ratio when using the system in actual BNCT applications are also discussed.


Assuntos
Terapia por Captura de Nêutron de Boro/instrumentação , Câmaras gama , Radiometria/instrumentação , Tomografia Computadorizada de Emissão de Fóton Único/instrumentação , Desenho de Equipamento , Análise de Falha de Equipamento , Estudos de Viabilidade , Sistemas On-Line , Reprodutibilidade dos Testes , Sensibilidade e Especificidade
4.
Rev Sci Instrum ; 81(2): 02B724, 2010 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-20192464

RESUMO

In direct plasma injection scheme, the relation between the ion current from a laser ion source and the accelerated beam current by a radio-frequency quadrupole (RFQ) linac was studied by a series of the following analyses. First, ion current at beam extraction was calculated from measured plasma parameters using a scaling law. Second, the beam emittance at the entrance of acceleration electrode region was evaluated by the simulation of the ion extraction out of the ion source plasma using the result of the first calculation. Last, the accelerated beam current could be reproduced by the simulation of beam acceleration using the results of the second. The second calculation revealed the time variation in the injected beam parameter to the RFQ linac. Then it was proved that the time structure of the accelerated beam was different from that of the injection beam because the degree of the matching between the injected beam emittance and the RFQ acceptance varied with time.

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