Nanoparticle-to-vesicle and nanoparticle-to-toroid transitions of pH-sensitive ABC triblock copolymers by in-to-out switch.

An efficient way to achieve nanoparticle-to-vesicle transition of ABC triblock copolymers by in-to-out switch of the pH-sensitive core-forming C block is described.

[Transperineal puncture drug injection in the treatment of chronic prostatitis].

OBJECTIVE: To investigate the effect of transperineal puncture drug injection in the treatment of chronic prostatitis. METHODS: Forty cases of chronic prostatitis underwent transperineal puncture drug injection. Bacterial culture and antimicrobial agent sensitivity tests were conducted on the prostatic fluid of the patients. A sensitive antimicrobial agent was selected, mixed with lidocaine and dexamethasone, and injected transperineally into the prostate at intervals of 7 days and 4 times as one course. After one month, the effect was evaluated and the patients were followed up for 6 months. RESULTS: Among the 40 cases, the cure rate was 52.5% (21/ 40), the alleviation rate 40% (16/40), the nullify rate 7.5% (3/40) and the total effectivity rate 92.5%. No relapse was found in the 28 followed-up cases. CONCLUSION: Transperineal puncture drug injection is a safe and effective way in the treatment of chronic prostatitis.