Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 4 de 4
Filtrar
Mais filtros










Base de dados
Intervalo de ano de publicação
1.
Zhongguo Zhong Yao Za Zhi ; 32(11): 1031-4, 2007 Jun.
Artigo em Chinês | MEDLINE | ID: mdl-17672335

RESUMO

OBJECTIVE: To investigate the contents of glycyrrhizic acid in hejian decoction (mixed the traditional Chinese herbs together, then boiling them with water) and the fenjian decoction (boiling the single traditional Chinese herb with water separately, then mixed the abstracts) of Sanaotang (composed of Ephedra sinica, Prunus armeniaca and Glycyrrhiza uralensis) and to compare with their anti-bacterial activities in vitro. METHOD: A HPLC method was established with a Agilent Zorbax SB-C18 column (4. 6 mm x 250 mm, 5 microm), a mobile phase of acetonitrile-0.2% acetic acid solution (35:65), a flow rate of 1 mL x min(-1) and a detection wavelength of 254 nmn in order to determine the contents of glycyrrhizic acid minimal bacterial inhibitory concentration (MIC) and minimal bactericidal concentration (MBC) antagonized the common bacteria in different decoctions were rieasured in vitro by employing dilution method. RESULT: The average content of glycyrrhizic acid of the hejian decoction was higher than that of the fenjian decoction. The hejian decoction could display the inhibitory bactericidal activity to Aeruginosus bacillus, but the fenjian decoction could not. And to Staphylococcus aureus, the inhibitory bactericidal activity the hejian decoction was slightly stronger than that of the fenjian decoction. CONCLUSION: Comparing with that of the fenjian decoction, the content of glycyrrhizic acid of the hejian decoction was higher and the anti-bacterial activities was stronger.


Assuntos
Antifúngicos/farmacologia , Cromatografia Líquida de Alta Pressão/métodos , Medicamentos de Ervas Chinesas/química , Ácido Glicirrízico/análise , Ácido Glicirrízico/farmacologia , Antibacterianos/análise , Antibacterianos/farmacologia , Antifúngicos/análise , Aspergillus niger/efeitos dos fármacos , Aspergillus niger/crescimento & desenvolvimento , Bactérias/efeitos dos fármacos , Bactérias/crescimento & desenvolvimento , Combinação de Medicamentos , Medicamentos de Ervas Chinesas/isolamento & purificação , Ephedra sinica/química , Glycyrrhiza uralensis/química , Temperatura Alta , Testes de Sensibilidade Microbiana , Plantas Medicinais/química , Prunus/química , Pseudomonas aeruginosa/efeitos dos fármacos , Pseudomonas aeruginosa/crescimento & desenvolvimento , Staphylococcus aureus/efeitos dos fármacos , Staphylococcus aureus/crescimento & desenvolvimento
2.
Zhongguo Zhong Yao Za Zhi ; 32(24): 2600-3, 2007 Dec.
Artigo em Chinês | MEDLINE | ID: mdl-18338596

RESUMO

OBJECTIVE: To investigate the factors influencing on the ephedrine contents in different compositions of Maxingshigan decoction. METHOD: Adopt mixed uniform design to dismantle recipes, employ the stepping regression analysis to deal with experimental statistics, use the partial correlational analysis to analyze the correlation coefficients and the results were validated. RESULT: The regressive equation was of significance, that is Y = 4.36719347 + 7.752707437X1 + 1.2557197041X3 (r = 0.85564, P = 0.0189). The main influencing factors on ephedrine content in Maxingshigan decoction were gypsum and amygdalin. The influent factor of amygdalin on ephedrine content had great significance, and gypsum had significance. CONCLUSION: The collective effects of amygdalin and gypsum affect the content of ephedrine in Maxing Shigan decoction which the content-effect relationship was in direct correlation.


Assuntos
Amigdalina/química , Sulfato de Cálcio/química , Medicamentos de Ervas Chinesas/química , Ephedra sinica/química , Efedrina/análise , Amigdalina/isolamento & purificação , Combinação de Medicamentos , Medicamentos de Ervas Chinesas/isolamento & purificação , Glycyrrhiza uralensis/química , Interações Ervas-Drogas , Materia Medica/química , Plantas Medicinais/química , Prunus/química
3.
Zhong Yao Cai ; 30(9): 1128-30, 2007 Sep.
Artigo em Chinês | MEDLINE | ID: mdl-18236758

RESUMO

OBJECTIVE: To determine the contents of amygdalin in traditional and granular decoctions of Maxingshigan decoction. METHODS: The determination was carried out by HPLC with an ODS column and a mobile phase of water-methanol (23:77) at 215 nm. RESULTS: The content of amygdalin in traditional decoction of Maxingshigan Decoction was 17.74 mg/g and 24.80 mg/g in granular one. CONCLUSION: The content of glycyrrhizic acid in traditional decoction of Maxingshigan decoction is obviously higher than that in granular one.


Assuntos
Amigdalina/análise , Cromatografia Líquida de Alta Pressão/métodos , Medicamentos de Ervas Chinesas/química , Plantas Medicinais/química , Sulfato de Cálcio/química , Combinação de Medicamentos , Medicamentos de Ervas Chinesas/isolamento & purificação , Glycyrrhiza uralensis/química , Ácido Glicirrízico/análise , Reprodutibilidade dos Testes , Sementes/química
4.
Zhongguo Zhong Yao Za Zhi ; 27(4): 258-60, 2002 Apr.
Artigo em Chinês | MEDLINE | ID: mdl-12774366

RESUMO

OBJECTIVE: To compare the contents of baicalin in the raw medical material and the different prepared medical materials of Scutellaria baicalensis. METHOD: The contents of baicalin were determined by HPLC. Chromatographic conditions included Hypersil C18 column and the mobile phase consisting of a mixture of methanol-0.04% phosphoric acid (46:54). Baicalin was detected at 280 nm. The standard curve was linear in the range of 0.0280-4.6700 micrograms with correlation coefficient 1.0000. The average recovery of baicalin was 101.22% with RSD = 2.54% (n = 5). RESULT: The contents of baicalin were 6.80% in raw material, 6.00% and 6.73% in the different prepared medical materials of S. baicalensis respectively. CONCLUSION: The two different kinds of preparing methods can be used to the raw material of S. baicalensis.


Assuntos
Flavonoides/análise , Plantas Medicinais/química , Scutellaria baicalensis/química , Cromatografia Líquida de Alta Pressão , Temperatura Alta , Tecnologia Farmacêutica
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA
...