1.
Science
; 189(4205): 805-6, 1975 Sep 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-17777589
RESUMO
The sequential simplex algorithm, an efficient optimization strategy, rapidly improved reaction yield as a function of time and temperature in the synthesis of pi-C(5)H(5)Mo(CO)(2)CSN(CH(3))(2). The work demonstrates the feasibility and efficiency of the simplex design and suggests its application and usefulness in other syntheses.