Establishing a master's degree programme in bioinformatics: challenges and opportunities.

The development of the Bioinformatics MS degree program at the University of Illinois, the challenges and opportunities associated with such a process, and the current structure of the program is described. This program has departed from earlier University practice in significant ways. Despite the existence of several interdisciplinary programs at the University, a few of which grant degrees, this is the first interdisciplinary program that grants degrees and formally recognises departmental specialisation areas. The program, which is not owned by any particular department but by the Graduate College itself, is operated in a franchise-like fashion via several departmental concentrations. With four different colleges and many more departments involved in establishing and operating the program, the logistics of the operation are of considerable complexity but result in significant interactions across the entire campus.

Mapping of population density.

The Bureau of the Census listing of geographical coordinates of centroids of all enumeration districts together with population counts from the U. S. 1970 Census of Population was used to contruct via computer five nationwide geographical grids of population density with sector dimensions of 0.01, 0.02, 0.04, 0.1, and 0.25 degrees of latitude and longitude. The entire population of a district was assigned to a grid sector if the coordinates of the district centroid fell within the boundaries of the sector. The sectors were then rank-ordered according to population density, and listings were made of sector population, population density, geographical location, cumulative population, area of sector, and cumulative area. The five sets of data were synthesized into single equations describing population as a function of density in one case and of area in another. From these data it was found, for example, that about 800,000 people live in 19 sectors of 0.01-degree dimensions with a population density of 100,000 people per square mile or greater (nearly all in Manhattan); about 10 million live in 183 sectors of 0.02-degree dimensions with a population density of 23,000 per square mile or greater; and about half of the total U. S. population, that is, about 100 million people, reside within about 0.6 percent of the area of the United States, that is, within 20,000 square miles.Four representative displays of population density are shown for the Northeast Corridor, including isometric views and a contour map.