1.
Adv Healthc Mater
; 3(9): 1404-7, 2014 Sep.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24408515
RESUMO
Polymers in tune. Automated parallel polymer synthesis is developed to obtain libraries of macromolecular prodrugs of ribavirin, a broad-spectrum antiviral agent. As many as 10 identified lead polymer conjugates exhibit therapeutic efficacy matching that of the pristine drug and at the same time suppressed the origin of the main side effect of ribavirin.