RESUMO
EDS virus strain 127 did not induce clinical signs or gross lesions in susceptible chicks of various age groups and in adult cocks. Virus persistence in various internal organs and the rate of excretion of virus by experimentally-infected chicken declined rapidly with increasing age. Virus 127 was detectable in organs of young chicks up to 5 weeks post-infection and in their faeces up to 2 weeks post-infection. In adult birds virus 127 persisted in tissues for about 3 weeks and was excreted with faeces for only 1 week post-infection. Vaccination of adult cocks with an inactivated vaccine resulted in intermittent shedding of virus only within the first 4 days post-challenge; thus, in comparison to non-vaccinated chickens, vaccination reduced virus excretion in faeces to a major extent.
Assuntos
Anticorpos Antivirais/análise , Doenças das Aves/imunologia , Doenças das Aves Domésticas/imunologia , Vírus da Reticuloendoteliose/imunologia , Retroviridae/imunologia , Infecções Tumorais por Vírus/veterinária , Animais , Aves , Imunofluorescência , Alemanha Ocidental , Aves Domésticas , Testes de Precipitina , Infecções Tumorais por Vírus/imunologiaRESUMO
An infectious agent was isolated from livers, spleens and bone marrow of two black storks (Ciconia nigra L.) originating from the same source. Pathological lesions consisted of small whitish focal areas in livers, spleens and bone marrow. The isolated agent was sensitive to chloroform and its multiplication was inhibited by 5-iodine-2-deoxy-uridine. It passed filters with a pore diameter of 220 nm and greater but not 100 nm filters. Electron microscopic examination revealed numerous nucleocapsids with hollow capsomeres and few enveloped particles in the supernatant fluids of infected cultures. The nucleocapsids were calculated to have 162 capsomeres on their surface. Using the plaque reduction method for neutralisation tests no serological cross reactions could be detected between the stork herpesvirus and sera against Marek's disease virus, turkey herpesvirus, and the Lake Victoria cormorant, amazon parrot, eagle owl, and pigeon herpesviruses. It is concluded that the isolated virus is a member of the avian herpesvirus group and it is proposed to tentatively term it herpesvirus ciconiae (ciconia lat. stork).
