1.
FEBS Lett
; 349(2): 201-4, 1994 Aug 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-8050566
RESUMO
The alpha-subunits of the widely expressed G-proteins Gq and G11 indistinguishably activate beta-isoforms of phospholipase C. In this report we have tested whether differences exist in the activation of both G-proteins via phospholipase C-linked receptors. We found that bombesin and vasopressin, with very similar potencies and time dependencies, induce the activation of both Gq and G11 in Swiss 3T3 cells, suggesting that these G-proteins, at least in part, serve interchangable functions.