RESUMO
In the title compound, 4-amino-1-(2-deoxy-beta-D-erythro-pentofuranosyl)-1H-benzotriazole, C11H14N4O3, the conformation of the N-glycosidic bond is in the high-anti range [chi = -77.1 (4) degrees ] and the 2'-deoxyribofuranose moiety adopts a 2'-endo ((2)E) sugar puckering. The 5'-hydroxyl group is disordered and has conformations ap with gamma = 171.1 (3) degrees [occupation of 61.4 (3)%] and +sc with gamma = 52.4 (6) degrees [occupation of 38.6 (3)%]. The nucleobases are stacked in the crystal state.
Assuntos
Adenosina/análogos & derivados , Desoxiadenosinas/química , Desoxiadenosinas/análogos & derivados , Ligação de Hidrogênio , Conformação MolecularRESUMO
In the title compound, 2-amino-1-(2-deoxy-beta-D-erythro-pentofuranosyl)-5-methylpyrimidin++ +-4 (1H)-one, C(10)H(15)N(3)O(4), the conformation of the N-glycosidic bond is syn and the 2-deoxyribofuranose moiety adopts an unusual (O)T(1) sugar pucker. The orientation of the exocyclic C4'-C5' bond is +sc (+gauche).
