Assuntos
Hemangioma/patologia , Tumores Fibrosos Solitários/patologia , Neoplasias da Medula Espinal/patologia , Idoso , Biomarcadores Tumorais/análise , Diagnóstico Diferencial , Humanos , Imuno-Histoquímica , Masculino , Meningioma/patologia , Tumores Fibrosos Solitários/metabolismo , Neoplasias da Medula Espinal/metabolismoRESUMO
The authors describe their experience with the use of impression cytology (IC) as a diagnostic aid in the evaluation of external eye disorders. IC is shown to be useful for diagnosis of epithelial cell storage disorders, infectious diseases, and allergic disorders.
Assuntos
Oftalmopatias/diagnóstico , Olho/patologia , Infecções por Chlamydia/diagnóstico , Conjuntivite Bacteriana/diagnóstico , Técnicas Citológicas , Olho/ultraestrutura , Oftalmopatias/patologia , Herpes Zoster Oftálmico/diagnóstico , Humanos , Mucopolissacaridoses/diagnósticoRESUMO
Two patients developed graft versus host disease (GvHD) following allogeneic bone marrow transplantation for leukemia. One patient developed acute GvHD 12 days after transplantation, and the second developed chronic GvHD 100 days after transplantation. Tear analysis and conjunctival impression cytology were performed. The results were compared to a normal control and to another patient who was 18 months status post bone marrow transplantation with successfully treated GvHD. Tear sampling on the patient with chronic GvHD revealed greatly elevated IgG levels with an inverse IgG to IgA ratio, as compared with normals. In addition, two of three leukemia patients demonstrated decreased mucin levels in tears. Conjunctival impression cytology from the patient with chronic GvHD revealed an abundance of plasma cells.
Assuntos
Túnica Conjuntiva/patologia , Doença Enxerto-Hospedeiro/metabolismo , Imunoglobulina G/metabolismo , Plasmócitos/patologia , Lágrimas/metabolismo , Adulto , Cromatografia , Feminino , Doença Enxerto-Hospedeiro/patologia , Humanos , Imunoeletroforese , Imunoglobulina A/metabolismo , Imunoglobulina M/metabolismo , MasculinoRESUMO
A 69-year-old man of mixed racial background was discovered to have a large, deeply pigmented mass in his left eye with a history of rapid growth during the previous 6 months. The eye was enucleated, and histopathological examination revealed an epithelioid malignant melanoma arising from a melanocytoma.
Assuntos
Transformação Celular Neoplásica/patologia , Neoplasias da Coroide/patologia , Corpo Ciliar/patologia , Melanoma/patologia , Nevo Pigmentado/patologia , Neoplasias Uveais/patologia , Idoso , População Negra , Transformação Celular Neoplásica/ultraestrutura , Neoplasias da Coroide/etnologia , Neoplasias da Coroide/ultraestrutura , Corpo Ciliar/ultraestrutura , Humanos , Masculino , Melanoma/etnologia , Melanoma/ultraestrutura , Nevo Pigmentado/etnologia , Nevo Pigmentado/ultraestrutura , Neoplasias Uveais/etnologia , Neoplasias Uveais/ultraestrutura , População BrancaRESUMO
Paredrine has been used as an adjunct to the cocaine test for Horner's syndrome; however, there are no controlled studies measuring pupillary responses in normal eyes. Twenty-five volunteers with normal eye examinations received 1% Paredrine in one eye, followed by serial photography to document the extent of pupillary dilation. Pupillary measurements were taken from the photographs to prevent identification of the patient, control or treated eye, or the time after instillation of the eye drops. Lighter irides dilated more rapidly, and some patients with dark irides showed little response. The control eye showed progressive pupillary constriction as its fellow eye became more dilated.
