RESUMO
A young man presented with a chronic, persistent reticulated dermatosis involving the groin, genitals, and thighs that was refractory to therapy. Biopsy specimen revealed multiple cornoid lamellae consistent with porokeratosis. This clinical appearance has not been previously described, to our knowledge. The other clinical forms of porokeratosis and their histology are briefly reviewed.
Assuntos
Ceratose/patologia , Adulto , Biópsia , Humanos , Ceratose/diagnóstico , Masculino , Pele/patologiaRESUMO
Grover's disease (transient acantholytic dermatosis; TAD), a disorder of unknown etiology, may resemble Darier's disease and frequently resists conventional therapies. The lesions can be extensive and pruritus can be a prominent feature. Four patients with Grover's disease were treated with isotretinoin. Three patients with relatively acute disease responded with remissions of up to 10 months after treatment. One patient with disease of 8 months' duration obtained partial relief but experienced a relapse when medication was stopped.
Assuntos
Acantólise/tratamento farmacológico , Dermatopatias/tratamento farmacológico , Tretinoína/uso terapêutico , Acantólise/patologia , Feminino , Humanos , Isotretinoína , Masculino , Pessoa de Meia-IdadeRESUMO
A pityriasis rosea-like eruption developed in two acne patients receiving isotretinoin and gradually resolved once the dosage was reduced. Histologically the lesions, which were characterized by psoriasiform hyperplasia, bore no resemblance to pityriasis rosea. We believe the eruptions were a side effect of isotretinoin therapy.
Assuntos
Toxidermias/diagnóstico , Pitiríase/diagnóstico , Tretinoína/efeitos adversos , Acne Vulgar/complicações , Acne Vulgar/tratamento farmacológico , Adolescente , Adulto , Diagnóstico Diferencial , Toxidermias/etiologia , Toxidermias/patologia , Feminino , Humanos , Isotretinoína , Masculino , Pitiríase/patologiaRESUMO
A condition precipitated by acute sun exposure, occurring primarily in women, and having all the characteristics of erythema multiforme is reported.
Assuntos
Eritema Multiforme/etiologia , Transtornos de Fotossensibilidade/diagnóstico , Luz Solar/efeitos adversos , Doença Aguda , Eritema Multiforme/diagnóstico , Feminino , Humanos , Pessoa de Meia-Idade , Pele/patologiaRESUMO
A new treatment for geographic tongue with topically applied tretinoin is suggested and its effective use on three patients is described.