1.
Pharmacol Ther Dent
; 4(2-4): 59-64, 1979.
Artigo
em Inglês
| MEDLINE
| ID: mdl-296394
RESUMO
Tiodonium chloride was evaluated for its efficacy against Streptococcus mutans. Depending upon the concentration used, it was found to have either bacteriocidal or bacteriostatic activity against S mutans and ti inhibit the accumulation of plaque formed in vitro by this organism. When applied as a mouthrinse in hamsters infected with S mutans, tiodonium chloride significantly reduced the accumulation of dental plaque. Chlorhexidine gluconate was tested as a positive control in the in vivo experiment.