RESUMO
A new ent-kaurane diterpenoid glycoside (1), named glaucocalyxin G, has been isolated from the n-butanol-soluble fraction of the dried whole plants of Isodon japonica var. glaucocalyx along with two known compounds, namely arjunglucoside (2) and kaempferol-3-O-rutinoside (3). The structures of the isolated compounds were assigned on the basis of their (1)H and (13)C NMR spectra including two-dimensional NMR techniques such as HMQC, HMBC, and NOESY experiments and comparison with the literature data.
Assuntos
Diterpenos do Tipo Caurano/isolamento & purificação , Medicamentos de Ervas Chinesas/isolamento & purificação , Glicosídeos/isolamento & purificação , Isodon/química , Diterpenos do Tipo Caurano/química , Medicamentos de Ervas Chinesas/química , Glicosídeos/química , Quempferóis/química , Quempferóis/isolamento & purificação , Estrutura Molecular , Ressonância Magnética Nuclear Biomolecular , Folhas de Planta/químicaRESUMO
There are two mol-ecules in the asymmetric unit of the title compound, C(12)H(11)BrN(4)O. The dihedral angles between the pyrazole and pyrimidine rings are 1.28â (17) and 1.56â (17)° in the two mol-ecules. In one of the mol-ecules, the but-3-yn-yloxy side chain is disordered over two sets of sites in a 0.714â (8):0.286â (8) ratio.
