RESUMO
Pharmacomechanical thrombolysis is being used increasingly for the treatment of deep vein thrombosis (DVT) and aims to reduce the severity of post-thrombotic syndrome. We report the case of a 60-year-old woman with extensive lower limb DVT that was treated using pharmacomechanical thrombolysis leading to complete recovery of her deep venous system. The prompt use of pharmacomechanical thrombolysis for the acute management of extensive DVT should be considered when treating patients with extensive DVT in order to facilitate return of normal function.
Assuntos
Veia Ilíaca , Perna (Membro)/irrigação sanguínea , Veia Poplítea , Terapia Trombolítica/métodos , Trombose Venosa/terapia , Doença Aguda , Anticoagulantes/administração & dosagem , Cateterismo/métodos , Cateterismo Periférico/métodos , Feminino , Heparina/administração & dosagem , Humanos , Pessoa de Meia-Idade , Stents , Tomografia Computadorizada por Raios X , Ultrassonografia de Intervenção , Grau de Desobstrução Vascular/fisiologiaRESUMO
Apoptosis is a source of much research interest across many fields, including developmental biology, immunology and oncology. As the exact pathways of this process are identified, so too are potential avenues for therapeutic application. Death receptors are important in inducing apoptosis and together with their ligands have become a source of attention as potential therapeutic agents. This review provides an introduction to the role of death receptors in apoptosis, together with a look at possible areas where this information may be applied therapeutically.
