[Side effects of oral contraceptives in the first treatment cycle]. / Nebenwirkungen oraler Kontrazeptiva im ersten Einnahmezyklus.

In order to compare the secondary effects of oral contraceptive pills during the first cycle of application, 308 women between the age of 25 and 45 were interrogated by questionnaires about their subjective complaints. The patients received a contraceptive within an In-vitro-Fertilization-program (IVF-program) in preparation for a stimulation treatment to follow. The study consisted of two parts: at the beginning a pilot study was carried out in which retrospectively a pill containing 0.150 mg Desogestrel and 0.030 mg Ethinylestradiol and a contraceptive containing 0.075 mg Gestoden and 0.030 mg Ethinylestradiol were compared. In a following prospective randomized examination a product, new on the market, containing 0.250 mg Norgestimat and 0.035 mg Ethinylestradiol, was included. The most common secondary effects, occurring in 34% of our patients, were spottings and break through bleedings. Regarding the secondary effects--during the first cycle of application--no significant difference between the contraceptives could be established.

[Radioactive cesium 137 and cesium 134 in follicle and seminal fluid]. / Radioaktives Cäsium 137 und Cäsium 134 in der Follikel- und Samenflüssigkeit.

Radioactive caesium nuclids were measured in follicular fluid and seminal plasma after the nuclear power station accident of Chernobyl. Immediately after the event (June - Aug. 86) both Cs 137 and Cs 134 were negative, with the exception of one sample. Increased levels of Cs 137 were found in the next three periods of measurement (Nov. 86 - Jan. 87), (June - Aug. 87), (March 88), with the highest results one year after the accident. Increased levels of Cs 134 were found only in the last two periods of measurement. In seminal plasma, both Cs 137 and Cs 134, were elevated in some samples. An influence on the results of IVF was not registered.