Piezoelectric bone surgery for impacted lower third molar extraction compared with conventional rotary instruments: a systematic review, meta-analysis, and trial sequential analysis.

The aim of this study was to evaluate whether piezoelectric bone surgery (PBS) for impacted lower third molar extraction reduces the surgical time and risk of intra- and postoperative complications in comparison with conventional rotary instruments. This meta-analysis followed the PRISMA guidelines and was registered in the PROSPERO database. The PubMed, Embase, Scopus, and OpenGrey databases were screened for articles published from January 1, 1990 to December 31, 2018. Selection criteria included randomized controlled trials (RCTs) comparing PBS with conventional rotary instruments for impacted lower third molar extraction and reporting any of the clinical outcomes (intra- and postoperative complications and duration of surgery) for both groups. A risk of bias assessment was performed using the Cochrane Collaboration tool. A meta-analysis was performed, and the power of the meta-analytic findings was assessed by trial sequential analysis (TSA). Strong evidence suggests that PBS prolongs the duration of surgery and low evidence suggests that PBS reduces postoperative morbidity (pain and trismus) in comparison with rotary instruments. Data were insufficient to determine whether PBS reduces neurological complications and postoperative swelling in comparison with burs.

The efficacy of a porcine collagen matrix in keratinized tissue augmentation: a 5-year follow-up study.

BACKGROUND: When keratinized tissue width around dental implants is poorly represented, the clinician could resort to autogenous soft tissue grafting. Autogenous soft tissue grafting procedures are usually associated with a certain degree of morbidity. Collagen matrices could be used as an alternative to reduce morbidity and intra-operatory times. The aim of this study was to assess the efficacy of a xenogeneic collagen matrix as a substitute for soft tissue grafting around dental implants. METHODS: Fifteen consecutive patients underwent a vestibuloplasty and keratinized tissue reconstruction around dental implants, both in the mandible and the maxilla, with a porcine collagen matrix. The so obtained keratinized tissues were measured and evaluated after 6 months and 1, 4, and 5 years. RESULTS: The average gain of keratinized tissue was 5.7 mm. After 6 months, it was observed a resorption of 37%, after 1 year 48%, and after 5 years 59%. The mean gain of keratinized tissue after 5 years was 2.4 mm. Hemostatic effect and post-operative pain were evaluated too. All subjects referred minimal pain with no bleeding. No adverse reaction nor infection was noted. CONCLUSIONS: The present study showed the efficacy of a porcine collagen matrix in keratinized tissue augmentation. The possibility to use a soft tissue substitute is a great achievement as morbidity decreases and bigger areas can be treated in a single surgery.

The use of recombinant human bone morphogenetic protein-2 (rhBMP-2) in maxillofacial trauma.

In recent years, recombinant human bone morphogenetic protein-2 (rhBMP-2) has been introduced as a therapeutic option in the treatment of several congenital and acquired craniofacial defects. Although there have been promising clinical results, the international literature still lacks complete guidelines, including limits and indications for the use of rhBMP-2. The possible indications for rhBMP-2 in patients undergoing facial trauma are discussed in this article.

Overexpression of cyclin A in oral dysplasia: An international comparison and literature review.

Oral squamous cell carcinoma (OSCC) is one of the most debilitating cancers in the world and while its causes have been heavily researched, the outcome remains grim. Most of these cancers are identified in the late stage and as a result treatment options are limited. Therefore, researchers have focused their efforts on recognizing and identifying dysplastic tissue that has an increased chance of progressing to cancer. Research has begun to look at cell cycle dysfunctions and in particular, aberrant protein functions as a way of identifying the cellular mechanism at fault. The overexpression of a group of regulatory proteins called cyclins has been demonstrated in many types of dysplasia and carcinomas. Although researchers have identified several different types of cyclins as potential culprits, we chose to focus our study primarily on the overexpression of cyclin A. While most research on oral dysplasia and OSCC has been focused on cyclin D, studies have been done on cyclin A. While the etiology of oral dysplasia/SCC appears to be multifactorial, we chose to compare our results with those of similar studies performed across the globe. The social factors, such as the increased use of tobacco that may have contributed to our results, were compared with similar studies performed in Europe and Asia. While our results were remarkably similar and demonstrated a link between the overexpression of cyclin A in oral dysplasia, there exists some differences and thus may require a multicenter, longitudinal study.

Slow Orthodontic Teeth Extrusion to Enhance Hard and Soft Periodontal Tissue Quality before Implant Positioning in Aesthetic Area.

Approaching bone defects of jaws treatments, hard and soft tissue augmentation could be considered as a goal for clinicians when performing dental implant placement. The increase in patients who want cosmetic treatment puts practitioners in an awkward position when choosing the best therapy to obtain the most desirable results. A private dentist referred a young patient to the Department of Implantology in Milan in order to place implants in the upper jaw. Radiographic evaluation of the two upper anterior incisors confirmed that the teeth had a poor prognosis The anterior ridge volume was clinically analyzed and several therapeutic choices were evaluated. Rapid extractions and immediate implant positioning were not considered due to the vertical and horizontal components of the bone defect. Therefore, the surgical team decided on increasing the bone volume by using slow orthodontic teeth extrusion technique.After 3 months of orthodontic treatment, the angular intra-bony defects of 1.1 tooth was completely healed. Implant guided positioning, associated with a small bone graft, showed optimal results at the time of healing screw placement. The soft tissue conditioning was obtained by a provisional acrylic crown. The final application of two integral ceramic crowns showed excellent aesthetic results. Radiographic investigation at a 24 month follow-up confirmed the integration of the dental implants and the recovery of the bone defects. Several safe surgical techniques are available today for reconstructing atrophic jaws. However, the same technique applied on the posterior area did not give the same predictable results as in the anterior areas of the jaw.

Protein-Signaled Guided Bone Regeneration Using Titanium Mesh and Rh-BMP2 in Oral Surgery: A Case Report Involving Left Mandibular Reconstruction after Tumor Resection.

Recombinant human bone morphogenetic protein-2 (rhBMP-2) is an osteoinductive protein approved for use in oral and maxillofacial defect reconstruction. Growth factors act as mediators of cellular growth on morphogenesis and mythogenesis phases. Utilized as recombinant proteins, these growth factors need the presence of local target cells capable of obtaining the required results. This cell population may be present at the wound site or added to scaffolding material before implantation at the surgical site.The aim of this study is to evaluate the clinical and radiographic results of a reported case with a large bone defect, treated with an absorbable collagen sponge, rhBMP-2 and a titanium plate and mesh. The Authors want to report a case which shows the resulting effectiveness of the rhBMP2 action regarding a large, mandibular defect reconstruction. This case also shows how the removal of a rare tumor such as a ghost cell tumor of the jaw may be treated without harvesting bone from another body site. A quick diagnosis of the lesions is important in order to perform the most suitable treatment. The Authors also underline the clinical and histological steps to insure the correct treatment is carried out to solve the case.Moreover, from results obtained from this case, it is possible to highlight several clinical benefits for the patient by adding rhBMP-2 to the common allograft to not only have alveolar reconstruction defects and sinus floor augmentation, but also to have alveolar cleft reconstruction and to treat segmental defects.

Integration of the medical degree in oral and maxillofacial surgery: A 10-year follow-up.

PURPOSE: Ten years ago, the American Association of Oral and Maxillofacial Surgeons membership was surveyed to evaluate the influence that integration of a medical degree might have on oral and maxillofacial training. The intent of the current survey was to reassess the influence a medical degree has had on the specialty over the past 10 years. PATIENTS AND METHODS: The effects of a medical degree on privileges, referral patterns, and its role in the office, hospital, and academic settings were studied. Biographical data was collected and responses were evaluated for the following groups: 1) the nation as a whole, 2) MD versus non-MD oral and maxillofacial surgeons (OMS), 3) geographic regions of practice, 4) population, 5) number of years in practice, and 6) involvement in academic programs. RESULTS: The results of this survey were similar to the previous one. Substantially different responses were seen between the dual-degree and single-degree OMS as well as differences between geographic locations, years in practice, and academic involvement. MD-DDS and academic OMS again possessed a broader spectrum of privileges than their colleagues. Recently trained OMS again possessed a greater number of privileges than more experienced surgeons. CONCLUSION: Overall there has been a trend toward increasing surgical privileges over the past 10 years for both single- and dual-degree OMS. The results presented emphasize the need to continually assess the influence that a medical degree has on the specialty.

The use of palatal island flaps as an adjunct to microvascular free tissue transfer for reconstruction of complex oromandibular defects.

OBJECTIVE: To determine the efficacy of using palatal island flaps in combination with free tissue transfer for reconstruction of large, complex oral cavity defects. STUDY DESIGN: Prospective evaluation of patients with large, combined defects of the oral cavity reconstructed with palatal flaps in conjunction with microvascular free tissue transfer. METHODS: Elevation of a palatal flap was performed after completion of tumor resection. The flap was rotated and secured into place. A free flap was then harvested and inset to reconstruct the remaining oromandibular defect. Free flaps included the rectus abdominis (6), fibula (16), and radial forearm (6). RESULTS: Large complex oral cavity defects were repaired with a palatal island flap in conjunction with microvascular free tissue transfer in 28 consecutive patients. There were no complications associated with this flap. CONCLUSION: Maximal functional rehabilitation of large, complex oral defects requires independent reconstruction of the various regions of the oral cavity rather than single flap reconstruction. When used as an adjunct to free tissue transfer, the palatal island flap offers a reliable method for reconstructing large combination defects.

Reconstruction of superficial skin cancer defects of the nose.

PURPOSE: This article reviewed the results of reconstruction of surface nasal defects after removal of skin cancer. PATIENTS AND METHODS: One hundred patients with 103 surface defects involving various locations on the nose were treated. Management included direct closure, secondary epithelization, full-thickness skin grafts, and local flaps using 1 or 2 stages. RESULTS: Ten nasal defects were treated by direct closure, 8 defects healed by secondary epithelization, and 30 patients were treated with a full-thickness skin graft. Fifty-five defects were reconstructed with local flaps including 30 one-stage and 25 two-stage flaps. CONCLUSION: Many options are available for reconstructing nasal defects that can lead to acceptable aesthetic results. Among the factors that need to be addressed before choosing a procedure for reconstruction of surface nasal defects resulting from skin cancer are size and location of the defect, aesthetic concerns, and the medical status of the patient.

Single-stage CO2 laser assisted uvuloplasty for treatment of snoring and mild obstructive sleep apnoea.

PURPOSE: The purpose of this study was to describe a single-stage laser assisted uvuloplasty (uvulectomy) and to determine its effectiveness in treatment of snoring and mild obstructive sleep apnoea (OSA). PATIENTS AND METHODS: All patients treated with laser assisted uvuloplasty in a 49-month period for snoring and/or mild OSA were studied. Frequency of snoring before and after surgery, loudness of snoring and postoperative discomfort were investigated. Patients were asked to evaluate change in daytime energy, sleep habits, missed days of work and also overall satisfaction following laser assisted uvuloplasty. RESULTS: Thirty patients underwent a single-stage laser assisted uvuloplasty. A preoperative diagnosis of OSA was established in 19 patients, the remaining 11 patients were treated for snoring. There were no complications and only one patient required an additional stage. A questionnaire was completed by 18 patients (10 patients diagnosed with sleep apnoea, and eight patients with snoring only). Preoperatively the frequency of snoring averaged 9.3 cm on a visual analogue scale. Postoperatively there were 12 patients with either none or very minimal snoring and six patients who had an average score of 3.2. Loudness of snoring also decreased from an average of 5.4 to 2.5 cm. Postoperative discomfort averaged 1.1 cm. Improvement in sleep was noted by 16 patients and improved daytime energy was noted by 17 patients. Eleven patients reported that they missed at least one day of work postoperatively with an average of 3 days missed. Patient satisfaction was reported by 17 patients with only one stating that he was unsatisfied with the procedure. CONCLUSIONS: Laser-assisted uvuloplasty (uvulectomy) is an effective surgical procedure for treatment of snoring and some types of OSA. A single-stage procedure appears to be effective and may further decrease the morbidity associated with this disease.

An algorithm for determination of ideal location of interdental osteotomies in presurgical orthodontic treatment planning.

Treatment-planning patients with dentofacial deformities begins with the desired final occlusal results in mind. Examination of occlusal models and subsequent feasibility model surgery determine whether segmentalization of one or both arches is necessary to accomplish the final occlusal scheme desired. Segmentalization of the maxilla and/or mandible may be used to resolve transverse or arch configuration discrepancies, level occlusal plane(s), correct dentoalveolar inclination, and/or remove extraction spaces by osteotomy. With so many variables to consider, it is often difficult even for an experienced clinician to systematically evaluate and select the ideal location of interdental osteotomies prior to presurgical orthodontics. This manuscript describes an algorithmic approach to diagnosis and treatment planning that will assist the clinician in determining the most favorable location(s) for interdental osteotomy(ies).

Tension forces in relation to LeFort III osteotomies.

Complications associated with LeFort III osteotomies have led to modifications of the procedure. Attempts to decrease morbidity include performing incomplete osteotomies or eliminating pterygomaxillary dysjunction. The purpose of this study was to determine the amount of tension required for separation of the midface from the pterygoid plates and to observe the fracture patterns. An Instron machine (Instron Corporation, Canton, MA) was used to measure the tension forces in 16 cadaver skulls divided into five groups. The groups varied as to whether the osteotomies were complete and whether pterygomaxillary separation was performed. Specimens with incomplete osteotomies and without pterygomaxillary separation required greater tension forces for separation and exhibited a high percentage (47%) of unfavorable fractures. Because high amounts of tension are required leading to unpredictable separations, we recommend complete osteotomies with pterygomaxillary dysjunction when performing LeFort III osteotomies.

Use of a locking reconstruction bone plate/screw system for mandibular surgery.

PURPOSE: This study examined the use of a locking reconstruction bone plate/screw system for use in mandibular surgery. PATIENTS AND METHODS: All patients treated with a locking reconstruction bone plate/screw system for fractures of the mandible or continuity defects in an 18-month period were prospectively studied. Ease of use of the locking plate/screw system, characteristics of the fractures/defects, and complications were tabulated. RESULTS: One hundred two locking bone plates were placed in 84 patients. Most patients (n=75) were treated for fractures of the mandible; there were eight continuity defects and one case of mandibular narrowing. There were no cases of malocclusion or difficulties encountered in using the plate/screw system. Loss of fixation was encountered in only one patient. CONCLUSIONS: The use of a locking plate/screw system was found to be simple, and it offers advantages over conventional bone plates by not requiring the plate to be compressed to the bone to provide stability.

Effect of configuration of surgical burs on osseointegration of dental implants: a pilot study.

Cannon burs with only one cutting surface and round burs with multiple cutting surfaces were evaluated in preparing bone sites for root form implant placement in five Macaca fascicularis monkeys. The cannon burs did not appear to produce a bone surface more conducive to osseointegration than the round burs. Bone cutting bur designs utilized in implant dentistry should be extensively evaluated and compared.