RESUMO
BACKGROUND: The combination of pulmonary fibrosis and emphysema (CPFE) has been recently defined as a syndrome, it is radiologically recognized and is characterized by the simultaneous coexistence of emphysema of superior pulmonary location and fibrosis predominantly in lower lobes. CASE PRESENTATION: We present three patients with CPFE, who underwent right cardiac catheterization for pulmonary hemodynamic assessment, finding mean pulmonary artery pressure (mPAP) between 37-52 mm Hg (mean 45 mm Hg), who received treatment with specific vasodilators for pulmonary arterial hypertension (PAH). DISCUSSION AND CONCLUSIONS: The three patients had higher mPAP than expected for Group III (Pulmonary hypertension due to lung disease and/or hypoxia) of the classification of pulmonary hypertension (PH) by the World Health Organization (WHO), in whom the use of Sildenafil was justified by the presence of progressive dyspnea, and no symptoms suggestive of infectious exacerbation associated with right ventricular failure.
Assuntos
Hipertensão Arterial Pulmonar , Enfisema Pulmonar , Fibrose Pulmonar , Cateterismo Cardíaco , Humanos , Hipertensão Pulmonar/diagnóstico , Hipertensão Pulmonar/tratamento farmacológico , Hipertensão Pulmonar/etiologia , Hipertensão Arterial Pulmonar/diagnóstico , Hipertensão Arterial Pulmonar/tratamento farmacológico , Hipertensão Arterial Pulmonar/etiologia , Enfisema Pulmonar/complicações , Enfisema Pulmonar/diagnóstico , Enfisema Pulmonar/diagnóstico por imagem , Fibrose Pulmonar/complicações , Fibrose Pulmonar/diagnóstico , Fibrose Pulmonar/diagnóstico por imagem , Citrato de Sildenafila/uso terapêutico , Vasodilatadores/uso terapêuticoAssuntos
COVID-19 , Hipertensão Pulmonar , Pneumonia , Humanos , Hipertensão Pulmonar/etiologia , SARS-CoV-2RESUMO
Klinefelter syndrome is a form of male hypogonadism due to testicular sclerohyalinosis with atrophy and azoospermia, which is the most common cause of male infertility. The syndrome is usually accompanied by metabolic, morphological, and neurobehavioral manifestations; Venous thromboembolic diseases such as deep vein thrombosis and pulmonary embolism. The existence of chronic thromboembolic pulmonary hypertension in patients with Klinefelter syndrome is scarce in the literature. We present the imaging and genetic analysis of a 37 -year-old male with a history of deep vein thrombosis who was admitted for exertional dyspnea.
Assuntos
Hipertensão Pulmonar , Síndrome de Klinefelter , Embolia Pulmonar , Trombose Venosa , Humanos , Masculino , Adulto , Síndrome de Klinefelter/complicações , Síndrome de Klinefelter/diagnóstico , Síndrome de Klinefelter/genética , Endarterectomia/métodos , Embolia Pulmonar/genética , Embolia Pulmonar/cirurgia , Embolia Pulmonar/complicações , Hipertensão Pulmonar/genética , Hipertensão Pulmonar/cirurgiaRESUMO
Portopulmonary hypertension (PoPH) is a vascular complication of portal hypertension. This study aims to identify the prevalence and analyzing the clinical and hemodynamic features of patients with PoPH from a cohort of pulmonary arterial hypertension (PAH) patients. A retrospective transversal descriptive and analytical study. Patients with PoPH taken from a PAH cohort. We compare with those reported in the literature. We found prevalence of 6.1% of 244 consecutive patients with PAH, 11 females and 4 males. The mean age was 62 years and the main etiology of portal hypertension was primary biliary cirrhosis. Statistical differences were found in mean pulmonary arterial pressure, pulmonary vascular resistance, right atrial pressure; we found levels lower than reported. We found significant differences in clinical and hemodynamic characteristics such as older age and hemodynamic parameters of less severity in the group of patients analyzed compared with reported data.
Assuntos
Hipertensão Arterial Pulmonar , Idoso , Feminino , Hemodinâmica , Humanos , Masculino , Pessoa de Meia-Idade , Prevalência , Hipertensão Arterial Pulmonar/epidemiologia , Hipertensão Arterial Pulmonar/fisiopatologia , Hipertensão Arterial Pulmonar/terapia , Estudos RetrospectivosRESUMO
RESUMEN. Presentamos el caso de un paciente masculino de 16 años de edad, con historia de fiebre no cuantificada con escalofríos y diaforesis de 1 semana de evolución; 4 días de presentar alteración de el estado de la conciencia, caracterizado por habla incoherente, desorientación en tiempo y espacio con período de mutismo, además 2 días de evacuaciones diarréicas tres veces al día amarillas, fétidas sin moco ni sangre. Se realizó hemocultivo donde se aisló salmonella entérica serotipo typhi, por lo que se manejó con Ceftriaxone por 7 días con evolución satisfactoria. Se destacan las manifestaciones clínicas neurológicas con las que debutó este caso
Assuntos
Infecções Bacterianas , Febre Tifoide , Salmonella enterica , Febre , Contaminação de AlimentosRESUMO
RESUMEN. Presentamos el caso de un paciente masculino de 16 años de edad, con historia de fiebre no cuantificada con escalofríos y diaforesis de 1 semana de evolución; 4 días de presentar alteración de el estado de la conciencia, caracterizado por habla incoherente, desorientación en tiempo y espacio con período de mutismo, además 2 días de evacuaciones diarréicas tres veces al día amarillas, fétidas sin moco ni sangre. Se realizó hemocultivo donde se aisló salmonella entérica serotipo typhi, por lo que se manejó con Ceftriaxone por 7 días con evolución satisfactoria. Se destacan las manifestaciones clínicas neurológicas con las que debutó este caso
