RESUMO
El liposarcoma es un tumor maligno de origen mesodermico derivado del tejido adiposo. Los tipos de liposarcoma según su diagnóstico histológico son: mixoide, pleomórfico, bien diferenciado y desdiferenciado. Puede llegar a alcanzar enormes proporciones, sobre todo cuando se localiza a nivel abdominal. Su tratamiento es la cirugía radical, si es posible, junto con radioterapia y/o quimioterapia. Se presentan cuatro pacientes diagnosticados de liposarcoma, un caso de liposarcoma bien diferenciado, otro caso de liposarcoma pleomórfico y dos casos de liposarcomas mixoides; con la característica de que uno de estos presento una recidiva local con una desdiferenciación del mismo. Los cuatro evolucionaron de forma diferente. Así su pronóstico va a depender de su variedad histopatológica y de una posible multicentricidad que dificulta la exéresis quirúrgica radical completa
The liposarcoma is a malignant tumor of mesodermic origin derived of the adipose tissue. Liposarcomas types, according to his histological diagnosis, are: mixoide, pleomorphic, well differentiated and dedifferentiated. It can get to reach enormous proportions, mainly when it is located at abdominal level. His treatment is the radical surgery, it is possible, together with radiation therapy and/or chemotherapy. Four patients diagnosed of liposarcoma are shown up, a case of liposarcoma well differentiated, another case of liposarcoma pleomorphic and two cases about liposarcoma mixoide; with the characteristic that one of these two cases presented a local recidivation with a dediferenciation of itself. The evolution of the four cases, was in a different way. So, their prognosis is going to depend on their histopathologic variety and on a possible multicentricidad that is going to difficult the complete radical surgical exeresis
